3,3'-[1,2-乙烷二基二(氧基)]二[2-甲基丙烯] | 50975-38-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3,3'-[1,2-乙烷二基二(氧基)]二[2-甲基丙烯]
• 中文别名: 二甲基烯丙基乙二醇二醚；3,3'-[1,2-乙二基二(氧代)]二[2-甲基丙烯]；二甲基烯丙基乙二醇双醚
• 英文名称: ethylene glycol bis(2-methylallyl) ether
• 英文别名: ethylene glycol dimethallyl ether；1,2-bis-methallyloxy-ethane；Aethylenglykol-bis-(2-methyl-allylaether)；1,2-Bis-methallyloxy-aethan；3,3'-[1,2-ethanediylbis(oxy)]bis[2-methylpropene]；3,3'-(1,2-Ethanediylbis(oxy))bis(2-methylpropene)；2-methyl-3-[2-(2-methylprop-2-enoxy)ethoxy]prop-1-ene
• CAS: 50975-38-7
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: XTGIWPVOMMMMJV-UHFFFAOYSA-N

物化性质

• 沸点：
  210.9±20.0 °C(Predicted)
• 密度：
  0.868±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2909199090

反应信息

• 作为反应物：
  描述：

  3,3'-[1,2-乙烷二基二(氧基)]二[2-甲基丙烯] 在 N-溴代丁二酰亚胺(NBS) 、 苯磺酰氯 、 sodium hydroxide 作用下， 以 1,4-二氧六环 为溶剂， 生成 2,9-Bis-bromomethyl-2,9-dimethyl-1,4,7,10,13-pentaoxa-cyclopentadecane
  参考文献：
  名称：

  脂肪酶催化反应合成C 2对称手性冠醚

  摘要：

  C 2对称的18冠-6二醇（rac - 1a）和15冠5二醇（rac - 1c）外消旋混合物的动力学拆分通过脂肪酶催化的乙酰化作用实现。使用（R）-（+）-1-（1-萘基）乙基铵盐酸盐作为位移试剂，通过1 H NMR光谱法测定手性冠二醇的对映体过量（95％ee和82％ee）。通过使用脂肪酶催化的溶剂分解动力学拆分外消旋二乙酸酯（rac - 2c），也可以获得C 2对称的手性15冠-5二醇（> 95％ee）。

  DOI：

  10.1016/j.tet.2011.09.119
• 作为产物：
  描述：

  3-溴-2-甲基丙烯 、 乙二醇 在 sodium hydroxide 作用下， 生成 3,3'-[1,2-乙烷二基二(氧基)]二[2-甲基丙烯]
  参考文献：
  名称：

  Nichols; Wrigley; Yanovsky, Journal of the American Chemical Society, 1946, vol. 68, p. 2021

  摘要：

  DOI：

文献信息

• Synthesis of bis(bromomethyl) dimethyl crown ethers and complexation properties of their derivatives having electron-donating sidearms
  作者：Yohji Nakatsuji、Tsuneharu Mori、Mitsuo Okahara

  DOI：10.1016/s0040-4039(01)81190-4

  日期：1984.1

  Several bis(bromomethyl) dimethyl 15-crown-5, 18-crown-6, and 21-crown-7 were prepared according to two methods without protecting reactive bromo substituents. Cis and trans isomers of la are separated and the structures are inferred by considering the complexation property of their derivatives having electron-donating sidearms toward sodium and potassium cations.

  根据两种方法在不保护反应性溴取代基的情况下制备了几种双（溴甲基）二甲基15-crown-5、18-crown-6和21-crown-7。分离Ia的顺式和反式异构体，并通过考虑其具有对钠和钾阳离子的供电子侧臂的衍生物的络合性质来推断结构。
• A New and Versatile Access to Polyazamacroheterocycles and Cryptands Through Ring-Closing Bis(hydroaminomethylation)
  作者：Christian L. Kranemann、Peter Eilbracht

  DOI：10.1002/1099-0690(200007)2000:13<2367::aid-ejoc2367>3.0.co;2-t

  日期：2000.7

  in the presence of primary amines or secondary α,ω-diamines has been applied to macroheterocyclic ring synthesis. Starting from (hetero)diallylic systems, 12- to 36-membered polyheterocycles have been readily obtained in up to 56% yield. In addition, we show that the macrocyclic systems thus obtained can be debenzylated and that the resulting macrocyclic diamines undergo a second ring-closing bis(hy

  在伯胺或仲α，ω-二胺存在下，Rh I催化的二烯加氢甲酰基化已用于大杂环合成。从（杂）二烯丙基体系开始，可以容易地以高达56％的产率获得12至36元的多杂环。另外，我们表明由此获得的大环系统可以被去苄基化，并且所得的大环二胺经历第二个闭环双（氢氨基甲基化）以产生穴状配体。
• Synthesis of Heterofunctionalised Diamines and Triamines by Hydroaminomethylation of Diallyl Ethers, -silanes, or -amines
  作者：Peter Eilbracht、Christian Ludger Kranemann、Lars Bärfacker

  DOI：10.1002/(sici)1099-0690(199908)1999:8<1907::aid-ejoc1907>3.0.co;2-s

  日期：1999.8

  Starting from diallyl ethers, -silanes, or -amines various di- or triamines with potential biological activity are obtainable in one step by RhI-catalysed hydroaminomethylation of the alkene moieties in the presence of synthesis gas.

  从二烯丙基醚，-silanes开始，或-胺各种二-或具有潜在生物活性三胺在一个步骤中获得的由铑我在合成气体的存在-催化的烯烃部分的hydroaminomethylation。
• PRODUCTION METHOD OF UNSATURATED (POLY)ALKYLENE GLYCOL ETHER MONOMER AND PRODUCTION METHOD OF (POLY)ALKYLENE GLYCOL CHAIN-CONTAINING POLYMER
  申请人：Yuasa Tsutomu

  公开号：US20100130793A1

  公开（公告）日：2010-05-27

  To provide a production method of a (poly)alkylene glycol chain-containing polymer which can be preferably used in various applications such as an admixture for cement and which can exhibit extremely high dispersibility to a cement composition. The unsaturated (poly)alkylene glycol ether monomer of the present invention is an unsaturated (poly)alkylene glycol ether monomer production method for producing an unsaturated (poly)alkylene glycol ether monomer by addition reaction of an alkylene oxide on an unsaturated alcohol, wherein the production method includes a step of carrying out addition reaction under condition of existence of 0.01 to 25 parts by mass of an unsaturated (poly)alkylene glycol diether monomer to 100 parts by mass of the unsaturated alcohol, and a (poly)alkylene glycol chain-containing polymer production method, wherein a monomer component including an unsaturated (poly)alkylene glycol ether monomer produced by the production method.

  提供一种生产（聚）烷基二醇链含聚合物的方法，该聚合物可用于各种应用，例如水泥掺合剂，并且能够对水泥组合物表现出极高的分散性。本发明的不饱和（聚）烷基二醇醚单体是一种不饱和（聚）烷基二醇醚单体生产方法，通过在不饱和醇上进行环氧化物的加成反应来生产不饱和（聚）烷基二醇醚单体，其中生产方法包括在100份质量的不饱和醇中存在0.01至25份质量的不饱和（聚）烷基二醇二醚单体的条件下进行加成反应的步骤，以及一种（聚）烷基二醇链含聚合物生产方法，其中包括由该生产方法生产的不饱和（聚）烷基二醇醚单体的单体组分。
• Pressure-sensitive medical sealant
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0318183A2

  公开（公告）日：1989-05-31

  A pressure sensitive medical sealant composition comprising a) a crosslinked, swellable polymeric matrix made from an N-vinyl lactam monomer and a multi-ethylenically unsaturated compound, wherein the ethylenic groups are vinyl groups, allyl groups or methallyl groups, which groups are bonded to nitrogen or oxygen atoms; b) a plasticizer; and c) an antimicrobial. The medical sealant is highly moisture vapor transmissive and is capable of incorporating large concentrations of iodine. The composition can be used in a variety of medical applications including as a teat plug, a wound or burn dressing, or as a sealant to seal junctions between medical instruments penetrating the skin and the skin. A method of preparing the medical sealant composition in a caulkable form is also disclosed.

  一种压敏型医用密封剂组合物，包括 a) 由 N-乙烯内酰胺单体和多乙烯不饱和化合物制成的交联、可溶胀的聚合物基体，其中乙烯基为乙烯基、烯丙基或甲基烯丙基，这些基团与氮原子或氧原子键合；b) 增塑剂；以及 c) 抗菌剂。这种医用密封剂具有很强的湿气透射性，并能掺入高浓度的碘。该组合物可用于多种医疗用途，包括用作乳头塞、伤口或烧伤敷料，或用作密封剂以密封穿透皮肤的医疗器械与皮肤之间的连接处。此外，还公开了一种制备可填塞形式的医用密封剂组合物的方法。