1-(4-Methyl-cyclohexyl)-propan-1-on | 90975-19-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(4-Methyl-cyclohexyl)-propan-1-on
• 英文别名: 1-Methyl-4-propionyl-cyclohexan；3-(4-Methyl-cyclohexyl)-propanon-(3)；1-(4-methyl-cyclohexyl)-propan-1-one；4-Methyl-hexahydropropiophenon；4-methylcyclohexyl ethyl ketone；1-(4-methylcyclohexyl)propan-1-one
• CAS: 90975-19-2
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: UAYNQGANCONQDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(4-Methyl-cyclohex-3-enyl)-propan-1-ol-2-on 在 platinum(IV) oxide 、 Pd/SrCO₃ 氢气 、 phosphorus pentoxide 作用下， 以 甲苯 为溶剂， 生成 1-(4-Methyl-cyclohexyl)-propan-1-on
  参考文献：
  名称：

  Kugatova-Shemyakina,G.P.; Vesa,V.S., Journal of general chemistry of the USSR, 1963, vol. 33, p. 3813 - 3820

  摘要：

  DOI：

文献信息

• NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS
  申请人：MetCalf, III Chester A.

  公开号：US20100184649A1

  公开（公告）日：2010-07-22

  The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

  本发明涉及新型脂肽化合物，这些化合物的药物组合物以及使用这些化合物作为抗菌化合物的方法。本发明的化合物特别适用于对抗各种细菌，包括耐药菌株。这些化合物可用作抗Clostridium difficile的抗菌剂。
• Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents
  申请人：Commercon Alain

  公开号：US20120244172A1

  公开（公告）日：2012-09-27

  The present invention relates to pyrrolo[1,4]benzodiazepine (PBD) dimer conjugates, to the compositions comprising them and to their therapeutic application, in particular as anticancer agents. The invention also relates to the process for the preparation of the conjugates, to their application as anticancer agents and to the dimers themselves.

  本发明涉及吡咯并[1,4]苯二氮䓬啉（PBD）二聚体共轭物，包括它们的组合物以及它们的治疗应用，特别是作为抗癌剂。该发明还涉及该共轭物的制备过程，以及它们作为抗癌剂的应用和二聚体本身。
• Bisoximether derivatives, methods and intermediate products for the production thereof, and their use for combating fungicidal pests and animal pests
  申请人：BASF Aktiengesellschaft

  公开号：US06414031B1

  公开（公告）日：2002-07-02

  There are disclosed bisoxime ether derivatives of the formula I in which the variables have the following meanings: R1 is halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C4-haloalkoxy; n is 1 to 5, it being possible for the radicals R1 to be different if n is other than 1; R2 is C1-C4-alkyl, C3-C6-alkenyl or C3-C6-alkynyl, it being possible for these groups to be partially or fully halogenated; Q is C(═CHOCH3)—COOCH3, C(═CHCH3)—COOCH3, C(═NOCH3)—COOCH3 or C(═NOCH3)13 CONHCH3; and salts thereof, processes and intermediates for the preparation of these compounds, and their use for controlling animal pests and harmful fungi.

  公开了式I的双肟醚衍生物，其中变量具有以下含义：R1是卤素，C1-C4-烷基，C1-C4-卤代烷基，C1-C4-烷氧基或C1-C4-卤代烷氧基；n为1至5，如果n不为1，则可能为基团R1不同；R2是C1-C4-烷基，C3-C6-烯基或C3-C6-炔基，这些基团可能部分或完全卤代；Q是C(═CHOCH3)—COOCH3，C(═CHCH3)—COOCH3，C(═NOCH3)—COOCH3或C(═NOCH3)13 CONHCH3；以及这些化合物的盐，制备这些化合物的过程和中间体，以及它们用于控制动物害虫和有害真菌的用途。
• DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：US20140031334A1

  公开（公告）日：2014-01-30

  A heterocyclic compound or a salt thereof represented by the formula (1): where R 2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or lower alkenylene group; and R 1 represents an aromatic group or a heterocyclic group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.

  一种由公式（1）表示的杂环化合物或其盐： 其中，R2表示氢原子或低级烷基基团；A表示低级烷基烯基基团；R1表示芳香基团或杂环基团。本发明的化合物具有广泛的治疗精神障碍，包括中枢神经系统障碍的光谱，无副作用和高安全性。
• New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents
  申请人：BRACCO IMAGING S.P.A

  公开号：US20150037261A1

  公开（公告）日：2015-02-05

  The present invention relates to a new class of diazepine-derivatives as chelating agents for paramagnetic metal ions, the process for their preparation, and use of such paramagnetic complexes as contrast agents, particularly suitable for Magnetic Resonance Imaging (MRI) analysis.

  本发明涉及一种新型的二氮杂环衍生物作为顺磁性金属离子螯合剂，其制备过程以及使用这种顺磁性金属离子复合物作为对比剂，特别适用于磁共振成像（MRI）分析。