1,6-bis[3-(3-carboxymethylphenyl)-4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxy)phenyl]hexane | 243120-89-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,6-bis[3-(3-carboxymethylphenyl)-4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxy)phenyl]hexane
• 英文别名: Diethyl 2,2'-(hexane-1,6-diylbis{6'-[(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)oxy]biphenyl-3',3-diyl})diacetate；ethyl 2-[3-[5-[6-[3-[3-(2-ethoxy-2-oxoethyl)phenyl]-4-[(2R,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyphenyl]hexyl]-2-[(2R,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetate
• CAS: 243120-89-0
• 化学式: C₆₆H₇₈O₂₄
• 分子量: 1255.33
• InChiKey: UCMXDJFDVQUZHE-MPGCQMRFSA-N

物化性质

• 沸点：
  1034.6±65.0 °C(Predicted)
• 密度：
  1.31±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  90
• 可旋转键数：
  39
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  300
• 氢给体数：
  0
• 氢受体数：
  24

反应信息

• 作为产物：
  描述：

  penta-O-acetyl-D-mannose 在 吡啶 、 氢氟酸 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 1,6-bis[3-(3-carboxymethylphenyl)-4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxy)phenyl]hexane
  参考文献：
  名称：

  Stereospecific α-d-mannosylation

  摘要：

  The stereospecific formation of alpha-D-mannosyl glycosidic linkages has been achieved in high yield using tetra-O-pivaloyl-alpha-D-mannopyranosyl fluoride and boron trifluoride diethyl etherate in dichloromethane. Examples of the alpha-D-mannosylation of primary, secondary, benzylic and phenolic hydroxyl groups are described. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(99)00065-8

文献信息

• Stereospecific α-d-mannosylation
  作者：Ian L. Scott、Robert V. Market、Russell J. DeOrazio、Harold Meckler、Timothy P. Kogan

  DOI：10.1016/s0008-6215(99)00065-8

  日期：1999.4

  The stereospecific formation of alpha-D-mannosyl glycosidic linkages has been achieved in high yield using tetra-O-pivaloyl-alpha-D-mannopyranosyl fluoride and boron trifluoride diethyl etherate in dichloromethane. Examples of the alpha-D-mannosylation of primary, secondary, benzylic and phenolic hydroxyl groups are described. (C) 1999 Elsevier Science Ltd. All rights reserved.