1,2-Dimethyl-4,5-diphenyl-imidazol | 16340-59-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,2-Dimethyl-4,5-diphenyl-imidazol
• 英文别名: 1,2-Dimethyl-4,5-diphenylimidazole
• CAS: 16340-59-3
• 化学式: C₁₇H₁₆N₂
• 分子量: 248.327
• InChiKey: BTSDBXHMQFVTNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  azomethane oxide 、 2,3-二苯基-2H-氮丙啶 在 三氟乙酸 作用下， 以 乙腈 为溶剂， 反应 6.0h， 以69%的产率得到1,2-Dimethyl-4,5-diphenyl-imidazol
  参考文献：
  名称：

  2H-叠氮与硝基的酸催化1，3-偶极环加成反应：意外获得1,2,4,5-四取代的咪唑。

  摘要：

  据报道，2H-叠氮基与硝酮的第一个1,3-偶极环加成反应是对1,2,4,5-四取代的咪唑进行区域选择性合成的直接方法。该三氟乙酸催化的方案可耐受多种脂族和芳族底物，在温和条件下，分离出的收率高达83％，可高效获得高度多样化的多取代咪唑。

  DOI：

  10.1021/acs.joc.9b03288

文献信息

• An efficient and one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by InCl3·3H2O
  作者：Saikat Das Sharma、Parasa Hazarika、Dilip Konwar

  DOI：10.1016/j.tetlet.2008.02.053

  日期：2008.3

  InCl3·3H2O was found to be a mild and effective catalyst for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles at room temperature. Moreover, the utility of this protocol was further explored conveniently for the one-pot, four component synthesis of 1,2,4,5-tetrasubstituted imidazoles in high yields.

  发现InCl 3 ·3H 2 O是在室温下高效，一锅，三组分合成2,4,5-三取代的咪唑的温和有效的催化剂。此外，可以方便地进一步探索该方案的实用性，以高产率一锅，四组分合成1,2,4,5-四取代的咪唑。
• Intermolecular interactions that determine the regioselectivity in 1,3-dipolar cycloadditions ofN-methyl-1,3-oxazolium-5-olates withN-(phenylmethylene)benzenesulphonamide
  作者：L. Bonati、R. Ferraccioli、G. Moro

  DOI：10.1002/poc.610080703

  日期：1995.7

  1,3-Dipolar cycloadditions of N-(phenylmethylene)benzenesulphonamide with mesionic N-methyl-1,3-oxazolium-5-olates give 2,5-disubstituted imidazole derivatives with high regioselectivity. The intermolecular interactions underlying this regioselectivity were investigated. The conformational and electronic properties of the reagents were characterized separately. The approach in the early stages of the

  N-（苯基亚甲基）苯磺酰胺的1，3-偶极环加成与N-甲基-1，3-恶唑鎓5-油酸酯的中性离子生成具有高区域选择性的2，5-二取代的咪唑衍生物。研究了这种区域选择性的分子间相互作用。分别对试剂的构象和电子性质进行了表征。然后通过考虑空间和静电分子相互作用对反应早期阶段的方法进行建模。通过扰动分子轨道（PMO）处理计算出了与不同反应路径有关的相互作用能，并进行了比较。
• VERNETZTE HOCHSTABILE ANIONENAUSTAUSCHERBLENDMEMBRANEN MIT POLYETHYLENGLYCOLEN ALS HYDROPHILER MEMBRANPHASE
  申请人：Between Lizenz GmbH

  公开号：EP3478750A1

  公开（公告）日：2019-05-08
• ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE
  申请人：Katakura Rie

  公开号：US20100045171A1

  公开（公告）日：2010-02-25

  Disclosed is an organic electroluminescent device having high external quantum efficiency and long emission life. Also disclosed are an illuminating device and a display, each comprising such an organic electroluminescent device. The organic electroluminescent device is characterized by comprising at least an anode and a cathode on a supporting substrate, while having at least one light-emitting layer between the anode and the cathode. The organic electroluminescent device is also characterized by containing a polymer which at least partially contains a compound A having a partial structure represented by the general formula (a) below and a reactive group, and is obtained by polymerizing the compound A through the reactive group. (In the formula, Ar1 and Ar2 respectively represent an aromatic ring.)
• ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME
  申请人：KATAKURA Rie

  公开号：US20110006670A1

  公开（公告）日：2011-01-13

  Disclosed is an organic electroluminescence element comprising an anode, a cathode and a plurality of organic compound layers between the anode and the cathode, provided that one of the organic compound layers is a light emitting layer containing a phosphorescence emitting compound, wherein at least one of the organic compound layers contains a compound represented by Formula (1), wherein, X represents O or S; Y 1 to Y 3 each represents a hydrogen atom, a substituent or a group represented by Formula (A) disclosed in the specification, provided that at least two of Y 1 to Y 3 are groups represented by Formula (A), not all of Y 1 to Y 3 are the same group, and at least one of the groups represented by Formula (A) has Ar of a carbazolyl group, or an azacarbazolyl group containing 2 to 5 nitrogen atoms.