3,5-二氟-4'-丙基-4-((3,4,5-三氟苯氧基)二氟甲基)联苯 | 303186-20-1

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3,5-二氟-4'-丙基-4-((3,4,5-三氟苯氧基)二氟甲基)联苯
• 中文别名: 4-[二氟(3,4,5-三氟苯氧基)甲基]-3,5-二氟-4'-丙基联苯；没查到；4-[二氟(3,4,5-三氟苯氧基)甲基]-3,5-二氟-4-n-丙基联苯
• 英文名称: 4-[difluoro(3,4,5-trifluorophenoxy)methyl]3,5-difluoro-4'-propylbiphenyl
• 英文别名: 4-(Difluoro(3,4,5-trifluorophenoxy)methyl)-3,5-difluoro-4'-propyl-1,1'-biphenyl；2-[difluoro-(3,4,5-trifluorophenoxy)methyl]-1,3-difluoro-5-(4-propylphenyl)benzene
• CAS: 303186-20-1
• 化学式: C₂₂H₁₅F₇O
• 分子量: 428.349
• InChiKey: YJUHXJQZJUQYJJ-UHFFFAOYSA-N

物化性质

• 熔点：
  42.511℃ (acetic acid )
• 沸点：
  431.6±45.0 °C(Predicted)
• 密度：
  1.332±0.06 g/cm3(Predicted)
• 溶解度：
  溶于甲醇
• LogP：
  6.5 at 25℃ and pH6.1

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为产物：
  描述：

  1-溴-3,5-二氟苯 在 2-双环己基膦-2',6'-二甲氧基联苯 、 四(三苯基膦)钯 、 iodine pentafluoride 、 potassium carbonate 、 triethylamine tris(hydrogen fluoride) 、 copper(l) chloride 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 正庚烷 、 N,N-二甲基乙酰胺 、 乙基苯 、 水 、 乙腈 为溶剂， 反应 11.0h， 生成 3,5-二氟-4'-丙基-4-((3,4,5-三氟苯氧基)二氟甲基)联苯
  参考文献：
  名称：

  オキシジフルオロメチレン骨格を有する化合物の製造方法

  摘要：

  本发明的问题在于提供一种通过简便的工艺，在不使用高毒性原料如二溴二氟甲烷的情况下，几乎不产生难以分离的杂质，并且以高收率制备具有氧二氟甲基骨架化合物的方法。解决方案是通过将硫醚羧酸酯（可以通过需要时与卤代硫醚羰化合物和特定化合物反应而获得）与由式：XF_n（其中，X代表氯、溴或碘，n代表1至5的自然数。）表示的化合物反应，可以高收率地获得具有氧二氟甲基骨架的化合物。此外，必要时，可以通过与硼酸化合物等反应，高收率地引入各种芳香环基等基团。【选定图】无

  公开号：

  JP2015193609A

文献信息

• NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION
  申请人：KONDOU TOMOYUKI

  公开号：US20070051919A1

  公开（公告）日：2007-03-08

  A liquid crystal (LC) compound having generally required physical properties, low viscosity, proper optical anisotropy, proper dielectric anisotropy and good compatibility with other LC compounds is described. An LC composition including the compound and an LCD device including the composition are also described. The compound is expressed by formula (1a): wherein the ring A 1 and the ring A 2 are independently 1,4-phenylene, pyridine-2,5-diyl, pyrimidine-2,5-diyl or naphthalene-2,6-diyl, in which any hydrogen can be replaced by halogen; Z 1 , Z 2 and Z 3 are independently a single bond, —(CH 2 ) 2 —, —(CH 2 ) 4 —, —CH═CH—, —C≡C—, —CF 2 O—, —OCF 2 —, —COO— or —OCO—; X a , X b , X c , X d , X e and X f are independently hydrogen or fluorine; Y is —OCH 2 F, —OCHF 2 , —OCF 3 , —SCH 2 F, —SCHF 2 , —SCF 3 , —CH 2 F, —CHF 2 , —CF 3 , fluorine or chlorine; L a and L b are independently hydrogen or fluorine; and “l” and “m” are independently equal to 0 or 1.

  描述了一种具有通常所需物理性质、低粘度、适当的光学各向异性、适当的介电各向异性以及与其他液晶化合物良好兼容性的液晶（LC）化合物。还描述了包括该化合物的LC组合物和包括该组合物的LCD装置。该化合物由式（1a）表示： 其中环A1和环A2分别为1,4-苯撑基、吡啶-2,5-二基、嘧啶-2,5-二基或萘-2,6-二基，其中任何氢可以被卤素取代；Z1、Z2和Z3分别为单键、—(CH2)—、—(CH2)4—、—CH═CH—、—C≡C—、—CF2O—、—OCF2—、—COO—或—OCO—；Xa、Xb、Xc、Xd、Xe和Xf分别为氢或氟；Y为—OCH2F、—OCHF2、—OCF3、—SCH2F、—SCHF2、—SCF3、—CH2F、—CHF2、—CF3、氟或氯；La和Lb分别为氢或氟；“l”和“m”分别独立地等于0或1。
• LIQUID CRYSTAL COMPOSITION CONTAINING NITROGEN-CONTAINING CYCLIC COMPOUND AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20160208172A1

  公开（公告）日：2016-07-21

  The disclosure shows a liquid crystal composition that contains a compound having an effect of preventing photolysis of the liquid crystal composition and having high solubility in the liquid crystal composition, and that satisfies at least one of characteristics such as high maximum temperature, low minimum temperature, small viscosity, suitable optical anisotropy, large positive or negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light or heat, and a suitable elastic constant, etc. and so on. The disclosure shows a liquid crystal composition that contains a compound having the following azolidine ring (Q-1) or azepane ring (Q-2), a liquid crystal display device and so on.

  该披露显示了一种液晶组合物，其中包含一种化合物，具有防止液晶组合物光解的效果，并在液晶组合物中具有较高的溶解度，并且满足以下特征之一，如高最高温度、低最低温度、粘度小、适当的光学各向异性、大正或负介电各向异性、大特定电阻、对紫外光或热稳定性高，以及适当的弹性常数等。披露显示了一种液晶组合物，其中包含具有以下氮杂环（Q-1）或氮杂环（Q-2）的化合物，液晶显示器件等等。
• LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXENE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20160280997A1

  公开（公告）日：2016-09-29

  A problem is to provide a liquid crystal compound satisfying at least one physical property such as high stability to heat and light, a high clearing point, low minimum temperature of liquid crystal phase, small viscosity, suitable optical anisotropy, large dielectric anisotropy, suitable elastic constant and excellent compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A solution is a compound represented by formula (1). R 1 is alkyl having 1 to 10 carbons, rings A 1 , A 3 and A 4 are independently 1,4-phenylene, ring A 2 is a divalent group represented by any one of formulas (Ch), (Cx) and (ch). Z 1 , Z 2 , Z 3 and Z 4 are a single bond, X 1 is fluorine, L 1 and L 2 are fluorine, a, b and c are independently 0 or 1, and a sum of a, b and c is 0 or 1, for example.

  问题是提供一种液晶化合物，满足至少一种物理性质，如高热稳定性和耐光性、高清晰点、液晶相的低最低温度、低粘度、适当的光学各向异性、大介电各向异性、适当的弹性常数以及与其他液晶化合物的优良兼容性，一种含有该化合物的液晶组合物和包括该组合物的液晶显示装置。解决方案是由式（1）表示的化合物。R1是具有1到10个碳的烷基，环A1、A3和A4分别是1,4-苯撑，环A2是由任一式（Ch）、（Cx）和（ch）中的任一式表示的二价基团。Z1、Z2、Z3和Z4是单键，X1是氟，L1和L2是氟，a、b和c分别独立地为0或1，a、b和c的总和为0或1，例如。
• Polymerizable compound having conjugated bonds, liquid crystal composition and liquid crystal display device
  申请人：JNC CORPORATION

  公开号：US10253259B2

  公开（公告）日：2019-04-09

  Subject It is to provide a polymerizable compound having a high polymerization reactivity, a high conversion yield and a high solubility in a liquid crystal composition, a polymerizable composition including this compound, a liquid crystal composite prepared from this polymerizable composition and a liquid crystal display device containing this composite. Means for solving the Subject A compound represented by formula (1), the liquid crystal composition and the liquid crystal display device. In the formula, for example, ring A1, ring A2 and ring A4 are phenylene or cyclohexylene; Sp1 and Sp2 are a single bond or alkylene having 1 to 6 carbons; Z1 and Z2 are —CH═CH— or —C≡C—; a is 1, b is 0; and P1 and P2 are a polymerizable group.

  提供一种具有高聚合反应性、高转化产率和在液晶组合物中具有高溶解度的可聚合化合物，包括该化合物的可聚合组合物，由该可聚合组合物制备的液晶复合物以及含有该复合物的液晶显示装置的主题的翻译。解决该主题的方法是通过公式（1）表示的化合物、液晶组合物和液晶显示装置。在该公式中，例如，环A1、环A2和环A4为苯基或环己基；Sp1和Sp2为具有1至6个碳原子的单键或烷基；Z1和Z2为—CH═CH—或—C≡C—；a为1，b为0；P1和P2为可聚合基团。
• COMPOUNDS HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES
  申请人：JNC CORPORATION

  公开号：US20170240809A1

  公开（公告）日：2017-08-24

  The invention provides a liquid crystal compound satisfying at least one of physical properties such as a high stability to heat or light, a high clearing point (or a high maximum temperature), a low minimum temperature of a liquid crystal phase, a small viscosity, a suitable optical anisotropy, a small dielectric anisotropy, a suitable elastic constant and a good compatibility with other liquid crystal compounds, a liquid crystal composition including this compound, and a liquid crystal display device containing this composition. The invention provdes a compound represented by formula (1): where R 1 and R 2 is alkyl having 1 to 20 carbons or the like; one of L 1 and L 2 is both hydrogens, and the other is both fluorines; Z 1 and Z 2 are independently a single bond, —COO—, —OCO—, —OCH 2 —, —CH 2 O—, —CF 2 O—, —OCF 2 —, —CH 2 CH 2 —, —CH═CH—, —C≡C— or the like.

  该发明提供了一种液晶化合物，满足以下至少一种物理性质：对热或光的高稳定性，高清晰点（或高最高温度），液晶相的低最低温度，低粘度，适当的光学各向异性，小介电各向异性，适当的弹性常数以及与其他液晶化合物的良好兼容性，包括这种化合物的液晶组合物，以及含有这种组合物的液晶显示装置。该发明提供了一种由以下式（1）表示的化合物：其中R1和R2是具有1至20个碳原子的烷基或类似物；L1和L2中的一个是两个氢，另一个是两个氟；Z1和Z2独立地是单键，—COO—，—OCO—，—OCH2—，—CH2O—，—CF2O—，—OCF2—，—CH2CH2—，—CH═CH—，—C≡C—或类似物。