3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethyleneoxy)benzyl alcohol | 575451-46-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethyleneoxy)benzyl alcohol
• 英文别名: 3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethylenoxy)benzyl alcohol；[3,5-Bis[2-[2-[4-[(4-ethenylphenyl)methoxy]phenoxy]ethoxy]ethoxy]phenyl]methanol；[3,5-bis[2-[2-[4-[(4-ethenylphenyl)methoxy]phenoxy]ethoxy]ethoxy]phenyl]methanol
• CAS: 575451-46-6
• 化学式: C₄₅H₄₈O₉
• 分子量: 732.871
• InChiKey: IDGDJYPOVWSNBU-UHFFFAOYSA-N

物化性质

• 熔点：
  105-107 °C(Solv: ethanol (64-17-5))
• 沸点：
  855.4±65.0 °C(Predicted)
• 密度：
  1.179±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  54
• 可旋转键数：
  25
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  94.1
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethyleneoxy)benzyl alcohol 在 四溴化碳 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 反应 0.33h， 以63%的产率得到3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethylenoxy)benzyl bromide
  参考文献：
  名称：

  Synthesis of periphery-functionalized dendritic polyethers

  摘要：

  New dendritic polyethers with bromo-, hydroxy- and vinyl-end groups have been synthesized by a convergent strategy. Planar, 1,3,5-trischlorocarbonylbenzene and 1,3,5-trihydroxybenzene, and tetrahedral, tetrakis(p-hydroxyphenyl)methane, cores have been used. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.12.003
• 作为产物：
  描述：

  4-氯甲基苯乙烯 在 氢氧化钾 、 四溴化碳 、 四丁基溴化铵 、 甲基三辛基氯化铵 、 potassium carbonate 、 三苯基膦 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 84.0h， 生成 3,5-bis(p-vinylphenylmethyloxy-p-phenyloxyethyleneoxyethyleneoxy)benzyl alcohol
  参考文献：
  名称：

  Synthesis of periphery-functionalized dendritic polyethers

  摘要：

  New dendritic polyethers with bromo-, hydroxy- and vinyl-end groups have been synthesized by a convergent strategy. Planar, 1,3,5-trischlorocarbonylbenzene and 1,3,5-trihydroxybenzene, and tetrahedral, tetrakis(p-hydroxyphenyl)methane, cores have been used. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.12.003

文献信息

• Polymer immobilization of bis(oxazoline) ligands using dendrimers as cross-linkers
  作者：Enrique Dı́ez-Barra、José M Fraile、José I Garcı́a、Eduardo Garcı́a-Verdugo、Clara I Herrerı́as、Santiago V Luis、José A Mayoral、Prado Sánchez-Verdú、Juan Tolosa

  DOI：10.1016/s0957-4166(03)00074-0

  日期：2003.4

  Homopolymers of bis(oxazoline) ligands can be used to prepare efficient catalysts for cyclopropanation reactions. However, the low accessibility to most bis(oxazoline) moieties leads to a low copper loading. As a consequence, the transmission of chiral information from the complexed polymer is not very efficient and only a few chiral cyclopropane molecules are obtained from each molecule of chiral ligand. The use of suitable dendrimers as cross-linkers in the polymerization process allows better copper functionalization. As a consequence the productivity of chiral cyclopropanes per molecule of chiral ligand greatly increases, which improves the ligand economy and the chirality transfer. (C) 2003 Elsevier Science Ltd. All rights reserved.