4,6-di-O-methyl-D-glucopyranose | 23313-26-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,6-di-O-methyl-D-glucopyranose
• 英文别名: 4,6-di-O-methylglucopyranoside；O⁴,O⁶-dimethyl-D-glucose；4,6-Dimethyl-α-D-glucose；4.6-Di-O-methyl-glucosid；4,6-Di-O-methylglucose；4,6-di-O-methyl-glucopyranose；(3R,4R,5S,6R)-5-methoxy-6-(methoxymethyl)oxane-2,3,4-triol
• CAS: 23313-26-0
• 化学式: C₈H₁₆O₆
• 分子量: 208.211
• InChiKey: PCFSZBHNMOUVLB-RTRLPJTCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88.4
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4,6-di-O-methyl-D-glucopyranose 、 乙酸酐 在 吡啶 作用下， 反应 12.0h， 生成 4,6-di-O-methyl-1,2,3-tri-O-acetyl-D-glucopyranose
  参考文献：
  名称：

  Adinolfi, M.; Barone, G.; Lanzetta, R., Canadian Journal of Chemistry, 1984, vol. 62, p. 1223 - 1226

  摘要：

  DOI：
• 作为产物：
  描述：

  (2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-3,5-dihydroxy-2-[(2R,3R,4S,5R,6R)-5-hydroxy-4-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy]oxan-2-yl]oxy-6-(hydroxymethyl)-2-[(1R,2S,4S,5'R,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxan-4-yl]oxyoxane-3,4,5-triol 、 (2S,3R,4R,5R,6R)-2-[(2R,3R,4S,5R,6R)-5-hydroxy-4-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy]oxan-2-yl]oxy-6-(hydroxymethyl)-2-[(1R,2S,4S,5'R,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 、 碘甲烷 生成 4,6-di-O-methyl-D-glucopyranose
  参考文献：
  名称：

  UNIYAI, G. C.;AGRAWAL, P. K.;THAKUR, R. S.;SATI, O. P., PHYTOCHEMISTRY, 29,(1990) N, C. 937-940

  摘要：

  DOI：

文献信息

• Steroid saponins and sapogenins ofAllium. XVII. The structure of karatavioside C
  作者：Yu. S. Vollerner、M. B. Gorovits、T. T. Gorovits、N. K. Abubakirov

  DOI：10.1007/bf00567288

  日期：——

  A new furostanol glycoside — karatavioside C (I) has been isolated from a methanolic extract of the inflorescences ofAllium karataviense Rgl. (family Liliaceae). By the complete acid hydrolysis, enzymatic hydrolysis, methylation, and reduction of compound (I), and also by the reduction of yuccagenin (II), the structure of the glycoside (I) has been established as 25(R)-furost-5-ene-2α, 3β, 22α, 26-tetrao]

  一种新的呋喃甾醇糖苷 — karatavioside C (I) 已从 Allium karataviense Rgl 的花序的甲醇提取物中分离出来。（百合科）。通过化合物(I)的完全酸水解、酶水解、甲基化和还原，以及通过丝兰素(II)的还原，糖苷(I)的结构已确定为25(R)-furost-5 -ene-2α, 3β, 22α, 26-tetrao] 26-0-β-D-吡喃葡萄糖苷 3-0-[0-β-D-吡喃葡萄糖苷-(1→2)][0-β-D-吡喃木糖苷-(1→3)]-0-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷。
• Steroidal Saponin from Polygonatum verticillatum
  作者：L. N. Gvazava、A. V. Skhirtladze

  DOI：10.1007/s10600-016-1859-1

  日期：2016.11

  New steroidal glycoside 1 was isolated by fractionation of total extracted compounds from rhizomes of Polygonatum verticillatum (Convallariaceae). Chemical transformations, physical constants, and spectral data characterized its structure as (25S)-spirost-5-en-3β-ol 3-O-β-D-glucopyranosyl-(1→3)-[β-Dfucopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside.

  新型甾体苷1是从轮叶黄精（黄精科）的根茎中提取的总化合物的分级分离中获得的。通过化学转化、物理常数和光谱数据，其结构被鉴定为（25S）-螺甾-5-烯-3β-醇 3-O-β-D-吡喃葡萄糖基-(1→3)-[β-D-吡喃岩藻糖基-(1→2)]-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷。
• Triterpenoid saponins from leaves of Pittosporum undulatum
  作者：Ryuichi Higuchi、Toshihiro Fujioka、Masayo Iwamoto、Tetsuya Komori、Toshio Kawasaki、Erich V. Lassak

  DOI：10.1016/0031-9422(83)80166-6

  日期：——
• Structure of desacylsaponins obtained from the bark of Quillaja saponaria
  作者：Ryuichi Higuchi、Yoshinori Tokimitsu、Toshihiro Fujioka、Tetsuya Komori、Toshio Kawasaki、David G. Oakenful

  DOI：10.1016/s0031-9422(00)81518-6

  日期：1986.12
• Steroid saponins and sapogenins ofAllium. XX. Structure of karatavisoides E and F
  作者：Yu. S. Vollerner、N. D. Abdullaev、M. B. Gorovits、N. K. Abubakirov

  DOI：10.1007/bf00574793

  日期：——