acridin-4-ylamine; hydrochloride | 3594-53-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: acridin-4-ylamine; hydrochloride
• 英文别名: Acridin-4-ylamin; Hydrochlorid；4-amino-acridine, monohydrochloride；Acridin-4-amine hydrochloride；acridin-4-amine;hydrochloride
• CAS: 3594-53-4
• 化学式: C₁₃H₁₀N₂*ClH
• 分子量: 230.697
• InChiKey: KXPWAMIDVCDUAE-UHFFFAOYSA-N

物化性质

• 熔点：
  >355 °C

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.9
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  acridin-4-ylamine; hydrochloride 、 苯胺 生成 acridin-4-yl-phenyl-amine
  参考文献：
  名称：

  123.氨基ac啶中氨基的性质。第二部分化学反应的证据

  摘要：

  DOI：

  10.1039/jr9430000458

文献信息

• Microbicidal compositions and methods and use
  申请人：Camus-Bablon Florence

  公开号：US20050037033A1

  公开（公告）日：2005-02-17

  The present invention is directed to microbicidal compositions containing a microbicidal formulation or agent and methods of use thereof for preventing the transmission of or treating sexually transmitted infections and/or common vaginal infections, while minimizing disruptions to vaginal ecology and epithelium. In a preferred embodiment, the microbicidal formulation or agent is ciclopirox olamine. These compositions are preferably encapsulated in the form of a foam, cream, wash, gel, suppository, ovule, lotion, ointment, film, tablet, foaming tablet, tampon, vaginal spray, or aerosol. Preferably the concentration of microbicidal agent is approximately 0.01% to approximately 50% by weight, more preferably between approximately 0.1% to approximately 28%, and most preferably between approximately 0.5% and approximately 5%.

  本发明涉及含有杀微生物制剂或制剂的杀微生物组合物及其使用方法，用于预防或治疗性传播感染和/或常见阴道感染，同时最大限度地减少对阴道生态和上皮的破坏。在一个优选的实施方案中，杀微生物制剂或制剂是环吡酮胺。这些组合物优选以泡沫、膏霜、洗液、凝胶、栓剂、胚珠、洗剂、软膏、薄膜、片剂、发泡片剂、棉条、阴道喷雾剂或气雾剂的形式封装。按重量计，杀菌剂的浓度最好在约 0.01%至约 50%之间，更优选在约 0.1%至约 28%之间，最优选在约 0.5%至约 5%之间。
• [EN] MICROBICIDAL COMPOSITIONS AND METHODS OF USE<br/>[FR] COMPOSITIONS MICROBICIDES ET PROCEDES D'UTILISATION
  申请人：PROGRAM FOR APPROPRIATE TECHNO

  公开号：WO2004105662A1

  公开（公告）日：2004-12-09

  The present invention is directed to microbicidal compositions containing a microbicidal formulation or agent and methods of use thereof for preventing the transmission of or treating sexually transmitted infections and/or common vaginal infections, while minimizing disruptions to vaginal ecology and epithelium. In a preferred embodiment, the microbicidal formulation or agent is ciclopirox olamine. These compositions are preferably encapsulated in the form of a foam, cream, wash, gel, suppository, ovule, lotion, ointment, film, tablet, foaming tablet, tampon, vaginal spray, or aerosol. Preferably the concentration of microbicidal agent is approximately 0.01% to approximately 50% by weight, more preferably between approximately 0.1% to approximately 28%, and most preferably between approximately 0.5% and approximately 5%.
• 123. The nature of the amino-group in aminoacridines. Part II. Evidence from chemical reactions
  作者：Adrien Albert、Bruce Ritchie

  DOI：10.1039/jr9430000458

  日期：——