(E)-N-(3-hydroxy-1-oxocyclopent-2-en-2-yl)-3-(4-hydroxy-3-methoxyphenyl) propenamide | 117820-36-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-N-(3-hydroxy-1-oxocyclopent-2-en-2-yl)-3-(4-hydroxy-3-methoxyphenyl) propenamide
• 英文别名: N-(3-Hydroxy-1-oxocyclopent-2-en-2-yl)-3-(4-hydroxy-3-methoxyphenyl)propenamide；(E)-3-(4-hydroxy-3-methoxyphenyl)-N-(2-hydroxy-5-oxocyclopenten-1-yl)prop-2-enamide
• CAS: 117820-36-7
• 化学式: C₁₅H₁₅NO₅
• 分子量: 289.288
• InChiKey: CFEPRQRWNQBOCI-XVNBXDOJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  95.9
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  (E)-N-(3-hydroxy-1-oxocyclopent-2-en-2-yl)-3-<4-(acetyloxy)-3-methoxyphenyl> propenamide 在 氨 作用下， 以 甲醇 为溶剂， 反应 0.5h， 以29%的产率得到(E)-N-(3-hydroxy-1-oxocyclopent-2-en-2-yl)-3-(4-hydroxy-3-methoxyphenyl) propenamide
  参考文献：
  名称：

  Synthesis of 2880-II, A Metabolite Related to Ferulic Acid

  摘要：

  A synthesis of 2880-II (1), a co-metabolite of colabomycin A (2) from Streptomyces griseoflavus, is described.

  DOI：

  10.1080/00397919108016756

文献信息

• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• Unsaturated amides derived from 2-amino-3-hydroxycyclopentenone: A stille approach to the synthesis of asuka-mABA, 2880-II, and limocrocin
  作者：Gregor Macdonald、Lilian Alcaraz、Xudong Wei、Norman J Lewis、Richard J.K Taylor

  DOI：10.1016/s0040-4020(98)00536-5

  日期：1998.8

  A Stille palladium catalysed vinyl halide-vinyl stannane or aryl stannane coupling approach to the title compounds is described. The 2-aminocyclopentanedione-derived vinyl bromides (12, n = 1, 2, 3) were prepared and coupled to synthesise 2880-II (4), a Streptomyces metabolite, asuka-mABA (6), obtained during investigations to elucidate the biogenesis of the antibiotic asukamycin, and limocrocin (10), a naturally occurring antibiotic and antiviral agent. (C) 1998 Elsevier Science Ltd. All rights reserved.
• EBENEZER, WARREN J., SYNTH. COMMUN., 21,(1991) N, C. 351-358
  作者：EBENEZER, WARREN J.

  DOI：——

  日期：——
• PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING
  申请人：ENEVOLV, INC.

  公开号：US20160186168A1

  公开（公告）日：2016-06-30

  The present disclosure provides compositions and methods for genomic engineering.
• US9944925B2
  申请人：——

  公开号：US9944925B2

  公开（公告）日：2018-04-17