(2S,3S,4R,6R)-6-cyclopentyloxy-2,4-dimethyl-3-triethylsilyloxyoxan-4-ol | 338387-44-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,4R,6R)-6-cyclopentyloxy-2,4-dimethyl-3-triethylsilyloxyoxan-4-ol
• CAS: 338387-44-3
• 化学式: C₁₈H₃₆O₄Si
• 分子量: 344.567
• InChiKey: UVOSPBMJLGGCOC-LEUOFYLZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.22
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  环戊醇 、 (2S,3S,4R,6R)-2,4-Dimethyl-6-phenylsulfanyl-3-triethylsilanyloxy-tetrahydro-pyran-4-ol 在 六氟磷酸银 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以88%的产率得到(2S,3S,4R,6R)-6-cyclopentyloxy-2,4-dimethyl-3-triethylsilyloxyoxan-4-ol
  参考文献：
  名称：

  Recent advances in the synthesis of 2-deoxy-glycosides

  摘要：

  Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom, occur widely in natural products and therefore have been the subject of intense synthetic activity. The report summarizes recent advances in this area, with a particular focus on work published since an earlier review on the topic, in 2000 (Marzabadi, C. H.: Franck, R. W. Tetrahedron 2000, 56, 8385-8417). (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.07.013

文献信息

• Recent advances in the synthesis of 2-deoxy-glycosides
  作者：Dianjie Hou、Todd L. Lowary

  DOI：10.1016/j.carres.2009.07.013

  日期：2009.10

  Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom, occur widely in natural products and therefore have been the subject of intense synthetic activity. The report summarizes recent advances in this area, with a particular focus on work published since an earlier review on the topic, in 2000 (Marzabadi, C. H.: Franck, R. W. Tetrahedron 2000, 56, 8385-8417). (C) 2009 Elsevier Ltd. All rights reserved.