(3RS,9R,10S)-panaxydol | 500763-15-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (3RS,9R,10S)-panaxydol
• 英文别名: panaxydol；8-[(2R,3S)-3-Heptyloxiran-2-yl]oct-1-en-4,6-diyn-3-ol
• CAS: 500763-15-5
• 化学式: C₁₇H₂₄O₂
• 分子量: 260.376
• InChiKey: GVLDSGIQZAFIAN-LRUHZDSUSA-N

物化性质

• 沸点：
  397.8±32.0 °C(Predicted)
• 密度：
  0.999±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  32.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (3RS,9R,10S)-panaxydol 在 manganese(IV) oxide 作用下， 以 二氯甲烷 为溶剂， 反应 0.67h， 以7.5 mg的产率得到人参炔E
  参考文献：
  名称：

  来自人参根部的聚乙炔

  摘要：

  摘要 从人参根正己烷提取物中分离得到5种新型聚乙炔，分别命名为A、B、C、D和E。这些结构是通过光谱和化学方法确定的。

  DOI：

  10.1016/0031-9422(91)83203-w
• 作为产物：
  描述：

  (2R,3S)-3-heptyloxirane methanol 在 N,N-二甲基丙烯基脲 、 正丁基锂 、 TEA 、 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 作用下， 以 四氢呋喃 为溶剂， 反应 17.0h， 生成 (3RS,9R,10S)-panaxydol
  参考文献：
  名称：

  Studies towards the Biomimetic Synthesis of Ginsenoyne L; Efficient Synthesis of 2'-epi-Ginsenoyne L

  摘要：

  DOI：

  10.3987/com-02-s25

文献信息

• Lifeforce liquid supplement
  申请人：Leitman Lorn

  公开号：US20110189319A1

  公开（公告）日：2011-08-04

  Two very important factors in human life—which play vital roles in promoting well being—includes returning the body to homeostasis and giving boost to body called lifeforce to get overall health free from diseases, i.e., its optimal balanced functioning ability. When the body is at homeostasis, there is no place for disease. It is only when the body is out of balance (something is deficient, in excess or stagnating) that pain, illness or disease can occur. The application described is based on returning the body to homeostasis (removing the problem and balancing the body) by providing lifeforce and not on dealing with the symptom (e.g., pain, vitamin deficiency). Imbalance results in various diseases and adverse health conditions (starting from aging to diabetes and cancers). This wonderful composition will interact with the body in a way that allows it to boost lifeforce and reach homeostasis no matter which direction it was. In this combination, in the form of liquid, all the 14 ingredients ( Lepidium meyenii (Maca), Croton planstigma (Dragon's blood) tree sap, Uncaria tomentosa (Cat's Claw), Morinda citrifolia (Noni fruit) 4:1 PE, Lutein, Lycopene 5%, Flaxseed Oil (Omega-3-Fatty Acids), Vinpocetine, Phosphatidyl Serine 50%, Korean Ginseng 80%, Bacopa monnieri (Bacopin), CDP Choline (Cognizing), Guaranine (Guarana Seed PE 12%), Yerba Mate Ext. 8%) work as mixture for returning the body to homeostasis and give it lifeforce.

  人类生活中两个非常重要的因素，对促进健康起着至关重要的作用，包括将身体恢复到稳态并提升被称为生命力的身体以获得健康，即其最佳平衡功能能力。当身体处于稳态时，疾病就无处容身。只有当身体失衡（某种物质缺乏、过量或停滞）时，疼痛、疾病或疾病才会发生。所描述的应用是基于将身体恢复到稳态（消除问题并平衡身体）并提供生命力，而不是处理症状（例如疼痛、维生素缺乏）。失衡会导致各种疾病和不良健康状况（从衰老到糖尿病和癌症）。这种神奇的组合将与身体互动，以一种方式让它增强生命力并达到稳态，无论它朝哪个方向。在这种液体形式的组合中，所有14种成分（Lepidium meyenii（玛卡）、Croton planstigma（龙血）树汁、Uncaria tomentosa（猫爪）、Morinda citrifolia（诺尼果）4：1提取物、叶黄素、番茄红素5%、亚麻籽油（Omega-3脂肪酸）、Vinpocetine、磷脂酰丝氨酸50%、韩国人参80%、Bacopa monnieri（Bacopin）、CDP胆碱（认知）、瓜拉宁（瓜拉纳籽提取物12%）、南美洲亚麻灌木提取物8%）作为混合物，用于将身体恢复到稳态并赋予生命力。
• Compounds, compositions and methods for modulating beta-amyloid production
  申请人：Active Pass Pharmaceuticals, Inc.

  公开号：US20030191144A1

  公开（公告）日：2003-10-09

  Methods and compositions useful in the treatment of amyloidosis and conditions and diseases associated therewith, such as Alzheimer's disease, are provided. The methods involve administering to a subject in need thereof a pharmaceutical composition including one or more agents that modulate PPAR&agr; and/or PPAR&dgr; activity, resulting in an inhibition of &bgr;-amyloid production and/or release from cells of the subject, particularly brain cells.

  提供了在治疗淀粉样变性及相关疾病和病况（如阿尔茨海默病）中有用的方法和组合物。这些方法涉及向需要治疗的对象施用包括一个或多个调节PPAR&agr;和/或PPAR&dgr;活性的药物组合物，导致抑制β-淀粉样蛋白从对象的细胞（尤其是脑细胞）中的产生和/或释放。
• Polyacetylenes from the roots of Panax ginseng
  作者：Kazuhiro Hirakura、Makoto Morita、Kaoru Nakajima、Yukinobu Ikeya、Hiroshi Mitsuhashi

  DOI：10.1016/0031-9422(91)83203-w

  日期：1991.1

  Abstract Five new polyacetylenes named ginsenoynes A, B, C, D and E were isolated from the hexane extract of the root of Panax ginseng . These structures were determined by spectral and chemical methods.

  摘要 从人参根正己烷提取物中分离得到5种新型聚乙炔，分别命名为A、B、C、D和E。这些结构是通过光谱和化学方法确定的。
• FUNCTIONAL FOOD COMPOSITION USING PROCESSED ANCHOVY PRODUCT AND MANUFACTURING METHOD THEREFOR
  申请人：Jang, Young Jin

  公开号：EP3861865A1

  公开（公告）日：2021-08-11

  The present invention relates to a functional food composition using an anchovy processed product and a method of manufacturing the same. More specifically, the present invention comprises the steps of: preparing a raw material food composition including semi-dried anchovies and raw anchovies; salting the raw material food composition; fermenting the salted food composition under a certain condition; extracting effective ingredients from the fermented food composition; purifying the extracted effective ingredients; and freeze-drying the purified effective ingredients.

  本发明涉及一种使用凤尾鱼加工产品的功能性食品组合物及其制造方法。更具体地说，本发明包括以下步骤：制备原料食品组合物，包括半干鳀鱼和生鳀鱼；将原料食品组合物盐渍化；在一定条件下发酵盐渍化的食品组合物；从发酵的食品组合物中提取有效成分；提纯提取的有效成分；以及冷冻干燥提纯的有效成分。
• Method of preparing red ginseng extract
  申请人：Daewoong Electric Industrial Co., Ltd.

  公开号：US20010028898A1

  公开（公告）日：2001-10-11

  A home-style decoctor endowed with steamy boiling function includes a main body equipped with a heater; a heating vessel; a support plate for allowing a to-be-boiled object to be placed above the surface of water stored in the heating vessel; means for supplying water for boiling into the heating vessel so that the to-be-object is immersed; a steam collector for gathering steam produced when the to-be-boiled object is decocted with water; means for condensing the steam collected into the steam collector; andsteam/condensed water guiding means for leading the steam present in the heating vessel to the steam collector and the condensed water placed in the steam collector to the heating vessel. With such construction, undried or white ginseng can become red ginseng extract by producing such useful components as several kinds of phenolic compounds and maltol, anti-oxidants, and ginsenosides Rg and Rh through steam-boiling, drying and re-boiling.

  一种具有蒸煮功能的家庭式煎煮器，包括一个装有加热器的主体；一个加热容器；一个支撑板，用于将待煮物体置于加热容器中储存的水的表面之上；向加热容器中提供用于煮沸的水的装置，以便将待煮物体浸入其中；蒸汽收集器，用于收集水煎煮待煮物体时产生的蒸汽；将收集到的蒸汽冷凝到蒸汽收集器中的装置；以及蒸汽/冷凝水导向装置，用于将加热容器中的蒸汽导向蒸汽收集器，并将蒸汽收集器中的冷凝水导向加热容器。有了这样的结构，未经干燥的人参或白参可通过蒸煮、干燥和再蒸煮产生多种酚类化合物和麦芽酚、抗氧化剂、人参皂苷 Rg 和 Rh 等有用成分，从而成为红参提取物。