Ethyl 2-[2,4-dimethylpent-3-en-2-yloxy(dimethyl)silyl]-2-phenylselanylacetate | 172913-59-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Ethyl 2-[2,4-dimethylpent-3-en-2-yloxy(dimethyl)silyl]-2-phenylselanylacetate
• CAS: 172913-59-6
• 化学式: C₁₉H₃₀O₃SeSi
• 分子量: 413.491
• InChiKey: NJNRDJNBGNWZJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.87
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ethyl 2-[2,4-dimethylpent-3-en-2-yloxy(dimethyl)silyl]-2-phenylselanylacetate 在 偶氮二异丁腈 、 三苯基氢化锡 作用下， 以 苯 为溶剂， 反应 1.0h， 生成 (3R,4R)-4-Isopropyl-2,2,5,5-tetramethyl-[1,2]oxasilolane-3-carboxylic acid ethyl ester
  参考文献：
  名称：

  Radical allylation of α-silylacetic esters

  摘要：

  Allylation of the radical generated from alpha-silyl-alpha-phenylselenoacetic esters with various allyltributyltin substrates led to good yields of the corresponding homoallylsilanes. A study on the nature of the radical thus generated was performed using comparative allylation rates with electronically different allyltributyltin compounds. Finally, these homoallylsilanes were converted into the corresponding homoallylic-1,2-diols after reduction of the ester function and oxidation of the C-Si bond.

  DOI：

  10.1016/0040-4020(95)00764-y
• 作为产物：
  描述：

  Ethyl 2-[chloro(dimethyl)silyl]acetate 在 正丁基锂 、 三乙胺 、 六甲基二硅氮烷 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 3.5h， 生成 Ethyl 2-[2,4-dimethylpent-3-en-2-yloxy(dimethyl)silyl]-2-phenylselanylacetate
  参考文献：
  名称：

  Radical allylation of α-silylacetic esters

  摘要：

  Allylation of the radical generated from alpha-silyl-alpha-phenylselenoacetic esters with various allyltributyltin substrates led to good yields of the corresponding homoallylsilanes. A study on the nature of the radical thus generated was performed using comparative allylation rates with electronically different allyltributyltin compounds. Finally, these homoallylsilanes were converted into the corresponding homoallylic-1,2-diols after reduction of the ester function and oxidation of the C-Si bond.

  DOI：

  10.1016/0040-4020(95)00764-y

文献信息

• Radical allylation of α-silylacetic esters
  作者：Yannick Landais、Denis Planchenault

  DOI：10.1016/0040-4020(95)00764-y

  日期：1995.10

  Allylation of the radical generated from alpha-silyl-alpha-phenylselenoacetic esters with various allyltributyltin substrates led to good yields of the corresponding homoallylsilanes. A study on the nature of the radical thus generated was performed using comparative allylation rates with electronically different allyltributyltin compounds. Finally, these homoallylsilanes were converted into the corresponding homoallylic-1,2-diols after reduction of the ester function and oxidation of the C-Si bond.