(4S,5S,11S)-5-O-(β-D-Xylopyranosyl)streptazolin | 321999-49-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4S,5S,11S)-5-O-(β-D-Xylopyranosyl)streptazolin
• 英文别名: 5-O-beta-D-Xylopyranosylstreptazolin；(4S,5S,6Z,11S)-6-ethylidene-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-3-oxa-1-azatricyclo[5.3.1.04,11]undec-7-en-2-one
• CAS: 321999-49-9
• 化学式: C₁₆H₂₁NO₇
• 分子量: 339.345
• InChiKey: ZYBDXIUZGXXAHC-BITYOMICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 (4S,5S,11S)-5-O-(β-D-Xylopyranosyl)streptazolin 在 吡啶 作用下， 反应 4.5h， 以69%的产率得到(4S,5S,11S)-5-O-(2',3',4'-Tri-O-acetyl-β-D-xylopyranosyl)streptazolin
  参考文献：
  名称：

  New Co-metabolites of the Streptazolin Pathway

  摘要：

  Variation of the culture conditions of Streptomyces sp. strain Al, which produces streptazolin (1), resulted in the isolation of four new co-metabolites: 5-O-(beta -D-xylopyranosyl)streptazolin (3), 9-hydroxystreptazolin (4), 13-hydroxystreptazolin (5), and streptenol E (6). Their structures were established by spectroscopic and chemical methods. The possible biosynthetic relationship between the streptazolins and the streptenols is discussed.

  DOI：

  10.1021/np000377i

文献信息

• New Co-metabolites of the Streptazolin Pathway
  作者：Carsten Puder、Shoshana Loya、Amnon Hizi、Axel Zeeck

  DOI：10.1021/np000377i

  日期：2001.1.1

  Variation of the culture conditions of Streptomyces sp. strain Al, which produces streptazolin (1), resulted in the isolation of four new co-metabolites: 5-O-(beta -D-xylopyranosyl)streptazolin (3), 9-hydroxystreptazolin (4), 13-hydroxystreptazolin (5), and streptenol E (6). Their structures were established by spectroscopic and chemical methods. The possible biosynthetic relationship between the streptazolins and the streptenols is discussed.