sapidolide A | 182191-87-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: sapidolide A
• 英文别名: 5,8-Methano-1,7-dioxacyclopent[cd]azulen-6(2H)-one, 9-ethenyloctahydro-4a,8a-dihydroxy-8b-methyl-, (2aS,4aR,5S,8R,8aS,8bS,9S)-；(1S,4S,7R,8S,11R,12S,13S)-13-ethenyl-1,7-dihydroxy-12-methyl-2,10-dioxatetracyclo[5.4.1.18,11.04,12]tridecan-9-one
• CAS: 182191-87-3
• 化学式: C₁₄H₁₈O₅
• 分子量: 266.294
• InChiKey: OZRZMHKATMSFPV-TWZLXLMISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 sapidolide A 在 吡啶 作用下， 反应 48.0h， 生成 sapidolide A mono acetate
  参考文献：
  名称：

  Sapidolide A: An unprecedented spherical carbocyclic lactone from Baccaurea sapida seed kernels: Is it a meroisoprenoid ?

  摘要：

  A novel tetrahydrofurano-lactone meroisoprenoid (sapidolide A) 1 has been isolated from a tropical plant Baccaurea sapida, and its structure has been determined on the basis of DEFT, H-1-H-1 COSY, H-1-C-13 COSY, (+)-FABMS, low energy EIMS, and ion desorption chemical ionization mass spectrometry, and was confirmed by X-ray crystallography of its single crystal. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)01480-3

文献信息

• Sapidolide A: An unprecedented spherical carbocyclic lactone from Baccaurea sapida seed kernels: Is it a meroisoprenoid ?
  作者：Manobjyoti Bordoloi、Nabin C. Barua、Srinivasa Mohan、Subhas C. Dutta、Raj K. Mathur、Anil C. Ghosh、Urszula Rychlewska

  DOI：10.1016/s0040-4039(96)01480-3

  日期：1996.9

  A novel tetrahydrofurano-lactone meroisoprenoid (sapidolide A) 1 has been isolated from a tropical plant Baccaurea sapida, and its structure has been determined on the basis of DEFT, H-1-H-1 COSY, H-1-C-13 COSY, (+)-FABMS, low energy EIMS, and ion desorption chemical ionization mass spectrometry, and was confirmed by X-ray crystallography of its single crystal. Copyright (C) 1996 Elsevier Science Ltd