(E)-1-ethyl 4-hydrogen 2-(1-phenylpropylidene)succinate | 93989-11-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-1-ethyl 4-hydrogen 2-(1-phenylpropylidene)succinate
• 英文别名: 3r-Aethoxycarbonyl-4-phenyl-hexan-(3)-saeure-(1)；(E)-3-ethoxycarbonyl-4-phenylhex-3-enoic acid
• CAS: 93989-11-8
• 化学式: C₁₅H₁₈O₄
• 分子量: 262.306
• InChiKey: XYNZYSYPHPGCMX-OUKQBFOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  苯丙酮 、 丁二酸二乙酯 在 sodium hydride 作用下， 生成 (Z)-1-ethyl 4-hydrogen 2-(1-phenylpropylidene)succinate 、 (E)-1-ethyl 4-hydrogen 2-(1-phenylpropylidene)succinate 、 (E)-1-ethyl 4-hydrogen 2-(1-phenylprop-1-enyl)succinate 、 (Z)-1-ethyl 4-hydrogen 2-(1-phenylprop-1-enyl)succinate
  参考文献：
  名称：

  Furan-2(3H)- and 2(5H)-ones. Part 5. Photoreactions of 3-benzylfuran2(5H)-ones; cyclisation to indenofuranones

  摘要：

  The effect of substitution at the 'central methane' on the photoreactivity of 3-benzylfuran-2(5H)ones 5a-g was investigated. Despite its di-pi-methane structure, photochemical arylation was effected to give substituted indenofuranones 6 in good yields. Only the substitution by phenyl caused the di-pi-methane rearrangement to give a cyclopropanofuranone 18g in moderate yield.

  DOI：

  10.1039/p19940001833

文献信息

• Furan-2(3H)- and 2(5H)-ones. Part 5. Photoreactions of 3-benzylfuran2(5H)-ones; cyclisation to indenofuranones
  作者：Osamu Muraoka、Genzoh Tanabe、Kyohko Sano、Toshie Minematsu、Takefumi Momose

  DOI：10.1039/p19940001833

  日期：——

  The effect of substitution at the 'central methane' on the photoreactivity of 3-benzylfuran-2(5H)ones 5a-g was investigated. Despite its di-pi-methane structure, photochemical arylation was effected to give substituted indenofuranones 6 in good yields. Only the substitution by phenyl caused the di-pi-methane rearrangement to give a cyclopropanofuranone 18g in moderate yield.