3-[双[2-(甲基丙烯酰氧基)乙基](甲基)铵基]丙烷-1-磺酸盐 | 1314713-40-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3-[双[2-(甲基丙烯酰氧基)乙基](甲基)铵基]丙烷-1-磺酸盐
• 英文名称: N,N-bis(methacryloxyethyl)-N-methyl-N-(3-sulfopropyl)ammonium betaine
• 英文别名: 3-[Bis[2-(methacryloyloxy)ethyl](methyl)ammonio]propane-1-sulfonate；3-[methyl-bis[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate
• CAS: 1314713-40-0
• 化学式: C₁₆H₂₇NO₇S
• 分子量: 377.459
• InChiKey: OFRYGBGGBLFQNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  25
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  118
• 氢给体数：
  0
• 氢受体数：
  7

安全信息

• 储存条件：
  2-8°C保存，充入氩气。

反应信息

• 作为产物：
  描述：

  N-甲基二乙醇胺 在 sodium methylate 作用下， 以 丙酮 为溶剂， 生成 3-[双[2-(甲基丙烯酰氧基)乙基](甲基)铵基]丙烷-1-磺酸盐
  参考文献：
  名称：

  Zwitterionic hydrogels crosslinked with novel zwitterionic crosslinkers: Synthesis and characterization

  摘要：

  Two novel zwitterionic sulfobetaine dimethacrylate crosslinkersN,N-bis(methacryloxyethyl)-N-methyl-N-(3-sulfopropyl)ammonium (CL1) and N,N-bis(methacryloxyethyl)-N-methyl-N-(4-sulfobutyl)ammonium (CL2) betaines were synthesized and used for preparation of zwitterionic hydrogels formed from N-(methacryloxyethyl)-N,N-dimethyl-N-(3-sulfopropyl)ammonium betaine (SBDMA) via redox-initiated free-radical polymerization. The commercially available crosslinkers N,N'-methylene bisacrylamide (BIS) and ethylene glycol dimethacrylate (EDMA) were also used. Equilibrium water content, sorption degree, diffusion coefficient of water, state of water, degree of crosslinking and mechanical properties were determined for hydrogels crosslinked using different crosslinking conditions. A minor difference in the spacer length between the charged moieties in CL1 and CL2 crosslinkers, respectively, was shown to influence the hydrogel properties. The CL1 and CL2 crosslinkers with chemical structure similar to SBDMA resulted in hydrogels with higher stiffness, mechanical strength and crosslink density compared to hydrogels crosslinked by BIS and EDMA. This difference was assigned to suppression of the compositional drift during the hydrogel formation when crosslinkers with chemical structure similar to monomer were used. PolySBDMA hydrogels exhibited a low adhesion of RAT-2 fibroblasts-like cells. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2011.04.056

文献信息

• AFFINITY POLYMERS AND METHODS FOR REDUCING PURINE LEVELS IN COMPLEX MIXTURES
  申请人：NITTO DENKO CORPORATION

  公开号：US20190329187A1

  公开（公告）日：2019-10-31

  This disclosure relates to an affinity polymer composite comprising a product of reacting a precursor mixture comprising at least one cross-linking monomer component having two or more ethenyl moieties suitable for polymerization; wherein the affinity polymer composite has a first binding energy with a purine compound that is at least 1 kcal/mole more favorable than a second binding energy with a flavor compound in a complex mixture. Some embodiments include a filtration medium comprising the affinity polymer composite described herein, wherein the affinity polymer composite has a primary particle diameter of about 45 micrometers to about 150 micrometers. Some embodiments include a filtration column comprising the filtration medium described herein. Some embodiments include a method for the removal of a purine compound from a complex mixture using the filtration medium described herein.
• Zwitterionic hydrogels crosslinked with novel zwitterionic crosslinkers: Synthesis and characterization
  作者：Peter Kasák、Zuzana Kroneková、Igor Krupa、Igor Lacík

  DOI：10.1016/j.polymer.2011.04.056

  日期：2011.6

  Two novel zwitterionic sulfobetaine dimethacrylate crosslinkersN,N-bis(methacryloxyethyl)-N-methyl-N-(3-sulfopropyl)ammonium (CL1) and N,N-bis(methacryloxyethyl)-N-methyl-N-(4-sulfobutyl)ammonium (CL2) betaines were synthesized and used for preparation of zwitterionic hydrogels formed from N-(methacryloxyethyl)-N,N-dimethyl-N-(3-sulfopropyl)ammonium betaine (SBDMA) via redox-initiated free-radical polymerization. The commercially available crosslinkers N,N'-methylene bisacrylamide (BIS) and ethylene glycol dimethacrylate (EDMA) were also used. Equilibrium water content, sorption degree, diffusion coefficient of water, state of water, degree of crosslinking and mechanical properties were determined for hydrogels crosslinked using different crosslinking conditions. A minor difference in the spacer length between the charged moieties in CL1 and CL2 crosslinkers, respectively, was shown to influence the hydrogel properties. The CL1 and CL2 crosslinkers with chemical structure similar to SBDMA resulted in hydrogels with higher stiffness, mechanical strength and crosslink density compared to hydrogels crosslinked by BIS and EDMA. This difference was assigned to suppression of the compositional drift during the hydrogel formation when crosslinkers with chemical structure similar to monomer were used. PolySBDMA hydrogels exhibited a low adhesion of RAT-2 fibroblasts-like cells. (C) 2011 Elsevier Ltd. All rights reserved.