4,7,10,13-tetraoxapentadecanoic acid triazol-β-D-galactopyranosyl-(1-4)-α-D-galactopyranoside | 1414786-72-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,7,10,13-tetraoxapentadecanoic acid triazol-β-D-galactopyranosyl-(1-4)-α-D-galactopyranoside
• 英文别名: 3-[2-[2-[2-[2-[4-[2-[(2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxyethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• CAS: 1414786-72-3
• 化学式: C₂₇H₄₇N₃O₁₇
• 分子量: 685.68
• InChiKey: KQEDUQMFRRUNFN-AOZKGXQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.6
• 重原子数：
  47
• 可旋转键数：
  23
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  284
• 氢给体数：
  8
• 氢受体数：
  19

反应信息

• 作为产物：
  描述：

  4,7,10,13-tetraoxapentadecanoic acid triazol-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1-4)-2,3,6-tri-O-acetyl-α-D-galactopyranoside 在 甲醇 、 sodium methylate 作用下， 反应 2.0h， 以91%的产率得到4,7,10,13-tetraoxapentadecanoic acid triazol-β-D-galactopyranosyl-(1-4)-α-D-galactopyranoside
  参考文献：
  名称：

  Functional assay for shiga-like toxin via detection by antibody capture and multivalent galabiose binding

  摘要：

  A functional detection assay was developed for Escherichia coli secreted shiga-like toxin based on antibody capture and visualization with a multivalent galabiose ligand. It was possible to detect verotoxin in medically relevant E. coli samples in a dose dependent fashion. This method is a new step towards measuring functional protein levels in complex mixtures, which can be used for diagnostic purposes in a clinical setting. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.10.053