5-methyl-7-trimethylsilylhept-6-yne-1,4-diol | 645614-98-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-methyl-7-trimethylsilylhept-6-yne-1,4-diol
• 英文别名: 5-Methyl-7-(trimethylsilyl)hept-6-yne-1,4-diol
• CAS: 645614-98-8
• 化学式: C₁₁H₂₂O₂Si
• 分子量: 214.38
• InChiKey: SOOLKTPEJDUDFE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.64
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  Trimethyl-[3-(tetrahydro-furan-2-yloxy)-but-1-ynyl]-silane 在 溴丁基-镁 、 六甲基磷酰三胺 、 manganese(ll) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 23.0h， 以76%的产率得到5-methyl-7-trimethylsilylhept-6-yne-1,4-diol
  参考文献：
  名称：

  Formation of manganese–alkyne complexes mediated by trialkylmanganates and their application

  摘要：

  Treatment of dodec-6-yne with triallylmanganate in the presence of 1,3,5-trimethylbenzene provides (Z)-dodec-6-ene. An addition of D2O before quenching the reaction affords the corresponding dideuterated alkene. The result suggests the existence of the manganese-alkyne complex as an intermediate. Treatment of methyl propargyl ethers as alkynes with tributylmanganate generates propargylmanganese species. The reaction of non-2-ynyl tetrahydropyran-2-yl ether with tributylmanganate provides tetradec-7-yn-1,5-diol and 6-hexylocta-6,7-dien-1,5-diol. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.09.077

文献信息

• Formation of manganese–alkyne complexes mediated by trialkylmanganates and their application
  作者：Toshihiro Nishikawa、Hiroshi Shinokubo、Koichiro Oshima

  DOI：10.1016/j.tet.2003.09.077

  日期：2003.11

  Treatment of dodec-6-yne with triallylmanganate in the presence of 1,3,5-trimethylbenzene provides (Z)-dodec-6-ene. An addition of D2O before quenching the reaction affords the corresponding dideuterated alkene. The result suggests the existence of the manganese-alkyne complex as an intermediate. Treatment of methyl propargyl ethers as alkynes with tributylmanganate generates propargylmanganese species. The reaction of non-2-ynyl tetrahydropyran-2-yl ether with tributylmanganate provides tetradec-7-yn-1,5-diol and 6-hexylocta-6,7-dien-1,5-diol. (C) 2003 Elsevier Ltd. All rights reserved.