| 1227254-94-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• CAS: 1227254-94-5
• 化学式: C₂₅H₂₁NO₄
• 分子量: 399.446
• InChiKey: NCMRKAJBCSAZGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.36
• 重原子数：
  30.0
• 可旋转键数：
  6.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  68.65
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  以 二苯醚 为溶剂， 生成
  参考文献：
  名称：

  Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella

  摘要：

  A series of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates were designed and synthesized. Their structures were confirmed by (1)H NMR, (13)C NMR, IR and HRMS. The biological activities were primarily evaluated against Eimeria tenella according to Anticoccidial Index (ACI) method in vivo. The results showed that compounds 5e, 5f and 5I exhibited anticoccidial activities against E. tenella at 27 mg kg(-1). (C) 2009 Yu Liang Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2009.12.006