3-氯-降冰片-2-烯-2-羧酸 | 101252-68-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 中文名称: 3-氯-降冰片-2-烯-2-羧酸
• 英文名称: 3-chloro-norborn-2-ene-2-carboxylic acid
• 英文别名: 3-Chlor-norborn-2-en-2-carbonsaeure；3-Chlorobicyclo[2.2.1]hept-2-ene-2-carboxylic acid
• CAS: 101252-68-0
• 化学式: C₈H₉ClO₂
• 分子量: 172.611
• InChiKey: VEZPNCWBGFZJMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  α-chloronorbornene 在 oxonium 、 叔丁基锂 作用下， 以 四氢呋喃 、 正戊烷 为溶剂， 生成 3-氯-降冰片-2-烯-2-羧酸
  参考文献：
  名称：

  Synthesis and reactions of 2-lithio-3-chlorobicyclo[2.2.1]hept-2-ene. Generation of the trimer of bicyclo[2.2.1]hept-2-yne

  摘要：

  DOI：

  10.1021/ja00542a041

文献信息

• Genetic and Biogeographic Relationships of the Invasive Round (Neogobius melanostomus) and Tubenose (Proterorhinus marmoratus) Gobies in the Great Lakes Versus Eurasian Populations
  作者：Alison K. Dillon、Carol A. Stepien

  DOI：10.1016/s0380-1330(01)70642-9

  日期：2001.1

  Population genetic structure and systematic relationships were investigated for two exotic fishes introduced to the Great Lakes in 1990, the round goby Neogobius melanostomus and the tubenose goby Proterorhinus marmoratus, using DNA sequences from the left domain of the mitochondrial DNA control region. Samples of round gobies were compared from different sites in the Great Lakes, an introduced population from the Gulf of Gdansk in Poland, and a native population from the northern Black Sea. The round goby was characterized by, relatively high genetic variability, and 17 haplotypes were identified from 64 individuals. Levels of genetic variation for the round goby were similar in the invasive and native sampling sites, suggesting relatively large founding populations and lack of bottlenecks. The northern Black Sea was eliminated as a probable founding source for both the Great Lakes and the exotic population in Poland. Substitutions in the left domain of the control region revealed significant differences among samples from the Great Lakes and Eurasia, and between Lakes Erie and St. Clair, suggesting non-random mating. No variation was detected in the tubenose goby population in the Great Lakes, which has been less successful in terms of spread and population growth. A molecular clock calibration suggested that the genera Neogobius and Proterorhinus diverged about 5.2 +/- 1.0 million years ago, apparently separating from a common ancestor shared with Gobius during the isolation of the Paratethys basin from the Mediterranean Tethys Sea.
• GASSMAN P. G.; GENNICK I., J. AMER. CHEM. SOC., 1980, 102, NO 22, 6863-6864
  作者：GASSMAN P. G.、 GENNICK I.

  DOI：——

  日期：——