25,26,27,28-tetrakis(hydrazinocarbonylmethoxy)-2,8,14,20-tetrathiacalix[4]arene | 1240283-60-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 25,26,27,28-tetrakis(hydrazinocarbonylmethoxy)-2,8,14,20-tetrathiacalix[4]arene
• CAS: 1240283-60-6；1240283-62-8
• 化学式: C₃₂H₃₂N₈O₈S₄
• 分子量: 784.919
• InChiKey: DKLAXQAFDFDHJL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.08
• 重原子数：
  52.0
• 可旋转键数：
  12.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  257.4
• 氢给体数：
  8.0
• 氢受体数：
  16.0

反应信息

• 作为反应物：
  描述：

  25,26,27,28-tetrakis(hydrazinocarbonylmethoxy)-2,8,14,20-tetrathiacalix[4]arene 、 3,5-二叔丁基-4-羟基苯甲醛 在 溶剂黄146 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 30.0h， 以87%的产率得到25,26,27,28-tetrakis{2-[N²-(3,5-di-tert-butyl-4-hydroxybenzylidene)hydrazino]-2-oxoethoxy}-2,8,14,20-tetrathiacalix[4]arene
  参考文献：
  名称：

  Synthesis of hydrazones containing sterically hindered phenol groups and tetrathiacalix[4]arene fragment

  摘要：

  1,3-Alternate and cone stereoisomers of tetrathiacalix[4]arene and 4-tert-butyltetrathiacalix[4]arene functionalized by carbohydrazide groups reacted with 3,5-di-tert-butyl-4-hydroxybenzaldehyde to give the corresponding hydrazones having sterically hindered phenol fragments.

  DOI：

  10.1134/s107042801210017x
• 作为产物：
  描述：

  25,26,27,28-Tetrakis[(ethoxycarbonyl)methoxy]-2,8,14,20-tetrathiacalix[4]arene 在 肼 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 36.0h， 以82%的产率得到25,26,27,28-tetrakis(hydrazinocarbonylmethoxy)-2,8,14,20-tetrathiacalix[4]arene
  参考文献：
  名称：

  Synthesis of new hydrazones based on tetrathiacalix[4]arene in the 1,3-alternate conformation

  摘要：

  Reactions of 1,3-alternate stereoisomers of tetrathiacalix[4]arene and 4-tert-butyltetrathiacalix[4]arene, functionalized by hydrazide groups, with benzaldehyde and pyridin-2-carbaldehyde gave new tetrathiacalix[ 4] arene tetrahydrazone derivatives as promising receptors for transition and toxic heavy metal ions.

  DOI：

  10.1134/s1070428010080087

文献信息

• Mercury(II) and silver(I) receptors based on tetrathiacalix[4]arene hydrazones
  作者：Sergey N. Podyachev、Nadezda E. Kashapova、Victor V. Syakaev、Svetlana N. Sudakova、Railya R. Zainullina、Margit Gruner、Wolf D. Habicher、Tatiana A. Barsukova、Fafu Yang、Alexander I. Konovalov

  DOI：10.1007/s10847-013-0307-0

  日期：2014.4

  The extraction ability of phenyl hydrazone derivatives of cone- and 1,3-alternate tetrathiacalix[4]arenes towards to some alkali, alkaline earth, transition and heavy metal ions has been investigated by picrate extraction method. The synthesized cone-tetrathiacalix[4]arene hydrazones show a high efficiency coupled with an excellent selectivity towards for Ag+ and Hg2+ ions. The stoichiometry of complexes and the extraction constants have been determined. The influence of calix[4]arene platform’s structure and the electron donor substituents in phenyl fragments on the extraction efficiency has been discussed.

  利用苦味酸盐萃取法研究了锥形和 1,3- 替位四硫杂[4]烷的苯基腙衍生物对一些碱金属、碱土金属、过渡金属和重金属离子的萃取能力。合成的锥四硫杂[4]烯酰肼对 Ag+ 和 Hg2+ 离子具有高效率和极佳的选择性。络合物的化学计量和萃取常数已经确定。讨论了钙[4]炔平台结构和苯基片段中电子供体取代基对萃取效率的影响。
• Pyridinyl hydrazone derivatives of thiacalix[4]arene as selective extractants of transition metal ions
  作者：Sergey N. Podyachev、Nadezda E. Burmakina、Victor V. Syakaev、Svetlana N. Sudakova、Wolf D. Habicher、Alexander I. Konovalov

  DOI：10.1007/s10847-010-9920-3

  日期：2011.10

  pyridinyl hydrazone derivatives of cone- and 1,3-alternate tetrathiacalix[4]arenes towards transition and alkali metals has been investigated by picrate extraction method. The stoichiometry of complexes and the extraction constants have been determined. It has been found that hydrazones do not extract alkali metal ions but show an excellent affinity towards transition and heavy metal cations. The removal

  用苦味酸盐萃取法研究了锥形和1,3-交替四硫杯[4]芳烃的吡啶基腙衍生物对过渡金属和碱金属的识别能力。复合物的化学计量和萃取常数已经确定。已经发现腙不提取碱金属离子，但对过渡金属和重金属阳离子表现出极好的亲和力。在锥形和 1,3- 替代异构体的情况下，从杯 [4] 芳烃平台中去除叔丁基会导致 d 离子提取选择性或效率的增加。