propyl 2-(1H-tetrazol-5-yl)acetate | 1443776-59-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: propyl 2-(1H-tetrazol-5-yl)acetate
• 英文别名: propyl 2-(2H-tetrazol-5-yl)acetate
• CAS: 1443776-59-7
• 化学式: C₆H₁₀N₄O₂
• 分子量: 170.171
• InChiKey: SXTGIEXRFFHVML-UHFFFAOYSA-N

物化性质

• 沸点：
  320.8±44.0 °C(Predicted)
• 密度：
  1.277±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  80.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  propyl 2-(1H-tetrazol-5-yl)acetate 、 生成
  参考文献：
  名称：

  四唑桥联双核铂（II）配合物的合成与构效关系：在四唑C5处的小修饰明显影响体内抗肿瘤功效。

  摘要：

  我们合成并表征了高抗癌活性铂（II）配合物[{cis-Pt（NH3）2} 2（μ-OH）（μ-tetrazolato-N2，N3）] 2+（5-HY ）在四唑C5处进行取代。然后，我们评估了对顺铂敏感和耐药的两种鼠淋巴细胞性白血病细胞系中总共23种衍生物的全面结构-细胞毒性关系。我们还报告了三种酯衍生物的体内抗肿瘤功效，其中两种对小鼠同种移植结肠26结直肠肿瘤的疗效比奥沙利铂高得多。

  DOI：

  10.1016/j.jinorgbio.2018.12.009
• 作为产物：
  描述：

  氰乙酸正丙酯 在 叠氮基三甲基硅烷 、 二乙酸二丁基锡 作用下， 以 苯 为溶剂， 反应 60.0h， 以99%的产率得到propyl 2-(1H-tetrazol-5-yl)acetate
  参考文献：
  名称：

  TMSN 3 -Bu 2的Sn（OAc）2：改性和用于Wittenberger四唑合成温和试剂系统

  摘要：

  各种腈与TMSN的处理3和卜2的Sn（OAc）2在30 ö下在苯60小时，得到相应的5-取代的1 ħ在良好-tetrazoles到优异的产率。该方法是温和有效的Wittenberger四唑合成的替代试剂系统，该系统在高温（93–110°C）下使用甲苯中的TMSN 3和Bu 2 SnO持续24–72 h。

  DOI：

  10.1016/j.tetlet.2019.151517

文献信息

• Organic semiconductor composition, organic thin-film transistor, electronic paper, and display device
  申请人：FUJIFILM Corporation

  公开号：US10008301B2

  公开（公告）日：2018-06-26

  The present invention provides an organic semiconductor composition, which improves the insulation reliability of an organic thin-film transistor without greatly reducing the mobility of the organic thin-film transistor, an organic thin-film transistor which is formed by using the organic semiconductor composition, and electronic paper and a display device which use the organic thin-film transistor. The organic semiconductor composition of the present invention contains an organic semiconductor material and an F-containing migration inhibitor selected from the group consisting of a compound represented by any of Formulae (1) to (8), a polymer compound (X) containing a repeating unit represented by Formula (A), and a polymer compound (Y) containing a repeating unit represented by Formula (B) and a repeating unit represented by Formula (C).

  本发明提供了一种有机半导体组合物，它能在不大大降低有机薄膜晶体管的迁移率的情况下提高有机薄膜晶体管的绝缘可靠性；提供了一种使用该有机半导体组合物形成的有机薄膜晶体管；还提供了使用该有机薄膜晶体管的电子纸和显示装置。本发明的有机半导体组合物含有一种有机半导体材料和一种含 F 的迁移抑制剂，该迁移抑制剂选自由式（1）至（8）中任一式所代表的化合物、含有式（A）所代表的重复单元的聚合物化合物（X）和含有式（B）所代表的重复单元和式（C）所代表的重复单元的聚合物化合物（Y）组成的组。
• Composition for forming gate insulating film, organic thin film transistor, electronic paper, and display device
  申请人：FUJIFILM Corporation

  公开号：US10014474B2

  公开（公告）日：2018-07-03

  The present invention provides a composition for forming a gate insulating film, which improves the insulation reliability of an organic thin film transistor without greatly reducing the mobility of the organic thin film transistor, an organic thin film transistor, electronic paper, and a display device. The composition for forming a gate insulating film of the present invention contains an insulating material and a migration inhibitor selected from the group consisting of a compound represented by any of Formulae (1) to (8), a polymer compound (X) containing a repeating unit represented by Formula (A), and a polymer compound (Y) containing a repeating unit represented by Formula (B) and a repeating unit represented by Formula (C).

  本发明提供了一种用于形成栅极绝缘膜的组合物，它能在不大大降低有机薄膜晶体管、有机薄膜晶体管、电子纸和显示装置的迁移率的情况下提高有机薄膜晶体管的绝缘可靠性。本发明用于形成栅极绝缘膜的组合物含有一种绝缘材料和一种迁移抑制剂，该迁移抑制剂选自由式（1）至（8）中任一式所代表的化合物、含有式（A）所代表的重复单元的聚合物化合物（X）和含有式（B）所代表的重复单元和式（C）所代表的重复单元的聚合物化合物（Y）组成的组。
• Efficient Transformation of Inactive Nitriles into 5-Substituted 1H-Tetrazoles Using Microwave Irradiation and Their Applications
  作者：Shinya Harusawa、Hiroki Yoneyama、Yoshihide Usami、Seiji Komeda

  DOI：10.1055/s-0032-1318476

  日期：——

  Efficient transformations of inactive nitriles into 5-substituted 1H-tetrazoles in DMF in a microwave reactor are described. The present method is applied to the synthesis of tetrazolato-bridged dinuclear platinum(II) complex and tetrazole C-1-ribonucleoside phosphoramidite.
• ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20160071624A1

  公开（公告）日：2016-03-10

  The present invention provides an organic semiconductor composition, which improves the insulation reliability of an organic thin-film transistor without greatly reducing the mobility of the organic thin-film transistor, an organic thin-film transistor which is formed by using the organic semiconductor composition, and electronic paper and a display device which use the organic thin-film transistor. The organic semiconductor composition of the present invention contains an organic semiconductor material and an F-containing migration inhibitor selected from the group consisting of a compound represented by any of Formulae (1) to (8), a polymer compound (X) containing a repeating unit represented by Formula (A), and a polymer compound (Y) containing a repeating unit represented by Formula (B) and a repeating unit represented by Formula (C).
• COMPOSITION FOR FORMING GATE INSULATING FILM, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20160087208A1

  公开（公告）日：2016-03-24

  The present invention provides a composition for forming a gate insulating film, which improves the insulation reliability of an organic thin film transistor without greatly reducing the mobility of the organic thin film transistor, an organic thin film transistor, electronic paper, and a display device. The composition for forming a gate insulating film of the present invention contains an insulating material and a migration inhibitor selected from the group consisting of a compound represented by any of Formulae (1) to (8), a polymer compound (X) containing a repeating unit represented by Formula (A), and a polymer compound (Y) containing a repeating unit represented by Formula (B) and a repeating unit represented by Formula (C).