3-Chloro-6-methoxyquinolin-4-amine | 1209537-50-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-Chloro-6-methoxyquinolin-4-amine
• CAS: 1209537-50-7
• 化学式: C₁₀H₉ClN₂O
• 分子量: 208.64
• InChiKey: NOFPZXGKTSMGJF-UHFFFAOYSA-N

物化性质

• 沸点：
  365.2±37.0 °C(Predicted)
• 密度：
  1.346±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  48.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NEW BICYCLIC ANTIBIOTICS
  申请人：Actelion Pharmaceuticals Ltd.

  公开号：EP1799676A2

  公开（公告）日：2007-06-27
• Bone Modulators And Methods Therewith
  申请人：Espina Virginia

  公开号：US20120065166A1

  公开（公告）日：2012-03-15

  THE INVENTION RELATES TO compositions, compounds, proteins and methods of treatment therewith. Aspects of embodiments also relate to a method of treating a patient by delivering to the tissues of said patient or administering to said patient a therapeutically effective amount of one or more compounds. Aspects of embodiments also relate to a method of detecting the presence of bone disease by machine-assaying detectable serotonin. Aspects of embodiments also relate to methods of treating disease in subjects.
• [EN] NEW BICYCLIC ANTIBIOTICS<br/>[FR] NOUVEAUX ANTIBIOTIQUES BICYCLIQUES
  申请人：ACTELION PERCUREX AG

  公开号：WO2006032466A2

  公开（公告）日：2006-03-30

  The invention relates to novel antibiotics of formula (I) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also represent CRa and, in the case of X, may also represent CRb; Ra represents halogen; Rb represents halogen or alkoxy; M is a linking chain containing a non-aromatic cyclic or heterocyclic group, and D represents alkyl, aryl or heteroaryl.