[(1R,2S,3S,4R,6S,9S,11R,12S,13S,14R,17S,19R,20S,21S,22R)-1,2,3,12,13,14,20,21,22-nonaacetyloxy-11,19-bis(acetyloxymethyl)-5,7,10,15,18,23,32-heptaoxatrispiro[5.2.59.2.517.116]tritriacontan-4-yl]methyl acetate | 1170693-10-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(1R,2S,3S,4R,6S,9S,11R,12S,13S,14R,17S,19R,20S,21S,22R)-1,2,3,12,13,14,20,21,22-nonaacetyloxy-11,19-bis(acetyloxymethyl)-5,7,10,15,18,23,32-heptaoxatrispiro[5.2.59.2.517.116]tritriacontan-4-yl]methyl acetate
• CAS: 1170693-10-3
• 化学式: C₅₃H₇₆O₃₁
• 分子量: 1209.17
• InChiKey: SSGJDOKMCDIMFM-XGNFDVIBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  84
• 可旋转键数：
  27
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  380
• 氢给体数：
  0
• 氢受体数：
  31

反应信息

• 作为产物：
  描述：

  、 乙酸酐 在 吡啶 作用下， 生成 [(1R,2S,3S,4R,6S,9S,11R,12S,13S,14R,17S,19R,20S,21S,22R)-1,2,3,12,13,14,20,21,22-nonaacetyloxy-11,19-bis(acetyloxymethyl)-5,7,10,15,18,23,32-heptaoxatrispiro[5.2.59.2.517.116]tritriacontan-4-yl]methyl acetate
  参考文献：
  名称：

  Transformation of linear oligoketosides into macrocyclic neoglycoconjugates

  摘要：

  The macrocyclization of linear D-galacto-2-heptulopyranose-containing oligoketosides has been carried out by intramolecular glycosidation and ring-closing metathesis. The aglycon fragment of the cyclic neglycoconjugates thus formed was an alkylidene or a polyether chain. One of the oligoketoside-crown ethers showed a moderate asymmetric induction in the Cram model phenyl acetate-acrylate addition. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.056