(6aS,8RS)-4-cyclopropyl-11-fluoro-8-[2-fluoro-4-((R)-5-hydroxymethyl-2-oxo-oxazolidin-3-yl)-phenoxymethyl]-8-hydroxy-1-oxo-1,4,6,6a,7,8,9,10-octahydro-5-oxa-4,10a-diaza-chrysene-2-carboxylic acid benzyl ester | 1029429-61-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (6aS,8RS)-4-cyclopropyl-11-fluoro-8-[2-fluoro-4-((R)-5-hydroxymethyl-2-oxo-oxazolidin-3-yl)-phenoxymethyl]-8-hydroxy-1-oxo-1,4,6,6a,7,8,9,10-octahydro-5-oxa-4,10a-diaza-chrysene-2-carboxylic acid benzyl ester
• 英文别名: benzyl (7S)-12-cyclopropyl-18-fluoro-5-[[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-5-hydroxy-15-oxo-9-oxa-2,12-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(18),10,13,16-tetraene-14-carboxylate
• CAS: 1029429-61-5
• 化学式: C₃₇H₃₅F₂N₃O₉
• 分子量: 703.696
• InChiKey: BTYLUMJYXPYCPE-GLBUXDGTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  51
• 可旋转键数：
  10
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  138
• 氢给体数：
  2
• 氢受体数：
  13

文献信息

• 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS
  申请人：Actelion Pharmaceuticals Ltd.

  公开号：EP2102217B1

  公开（公告）日：2012-02-15