| 1092110-65-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1092110-65-0
• 化学式: C₂₇H₃₉N₃O₆SSi
• 分子量: 561.775
• InChiKey: IJJMMKREVFWCKY-RMRNXIRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.31
• 重原子数：
  38.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  93.07
• 氢给体数：
  1.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  在 偶氮二异丁腈 、 三正丁基氢锡 作用下， 以 甲苯 为溶剂， 以94%的产率得到benzyl 2-acetamido-2,3-di-deoxy-4,6-O-(di-tert-butylsilandiyl)-α-D-glucopyranose
  参考文献：
  名称：

  Synthesis of Sugar Nucleotides by Application of Phosphoramidites

  摘要：

  A new method for the construction of pyrophosphates is reported based on the coupling of a sugar phosphate and a nucleoside phosphoramidite. The in situ formed phosphate-phosphite intermediate Was subsequently oxidized with tBuOOH. Three UDP-N-acetylglucosamine derivatives were prepared using this one-pot procedure in good yields.

  DOI：

  10.1021/jo802021t
• 作为产物：
  描述：

  benzyl 2-acetamido-2-deoxy-4,6-O-(di-tert-butylsilanediyl)-α-D-glucopyranose 、 N,N'-硫羰基二咪唑 以 甲苯 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  Synthesis of Sugar Nucleotides by Application of Phosphoramidites

  摘要：

  A new method for the construction of pyrophosphates is reported based on the coupling of a sugar phosphate and a nucleoside phosphoramidite. The in situ formed phosphate-phosphite intermediate Was subsequently oxidized with tBuOOH. Three UDP-N-acetylglucosamine derivatives were prepared using this one-pot procedure in good yields.

  DOI：

  10.1021/jo802021t