7-(((2R,3R,4S,5S)-3,4,5-trihydroxy-6-methylenetetrahydro-2H-pyran-2-yl)oxy)-3H-phenoxazin-3-one | 1356858-93-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7-(((2R,3R,4S,5S)-3,4,5-trihydroxy-6-methylenetetrahydro-2H-pyran-2-yl)oxy)-3H-phenoxazin-3-one
• CAS: 1356858-93-9
• 化学式: C₁₈H₁₅NO₇
• 分子量: 357.32
• InChiKey: XMWIJJQRODZYJV-XDNAFOTISA-N

物化性质

• 沸点：
  587.3±50.0 °C(predicted)
• 密度：
  1.61±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.62
• 重原子数：
  26.0
• 可旋转键数：
  2.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  122.25
• 氢给体数：
  3.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  7-(((2R,3R,4S,5S)-3,4,5-trihydroxy-6-methylenetetrahydro-2H-pyran-2-yl)oxy)-3H-phenoxazin-3-one 在 mercury dichloride 作用下， 以 水 为溶剂， 反应 0.25h， 生成 2-deoxy-scyllo-inosose
  参考文献：
  名称：

  A “Turn-on” Fluorescent Hg²⁺ Chemosensor Based on Ferrier Carbocyclization

  摘要：

  A "turn-on" fluorescent chemosensor with excellent selectivity and satisfactory sensitivity on Hg2+ detection in 100% water media has been established employing a carbohydrate based Ferrier carbocyclization reaction. The probe has also presented satisfactory results for the imaging of Hg2+ ions in cells and organisms.

  DOI：

  10.1021/ol2033477
• 作为产物：
  描述：

  (3S,4S,5R,6R)-2-methylene-6-((3-oxo-3H-phenoxazin-7-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate 在 sodium methylate 作用下， 以 甲醇 为溶剂， 以25 mg的产率得到7-(((2R,3R,4S,5S)-3,4,5-trihydroxy-6-methylenetetrahydro-2H-pyran-2-yl)oxy)-3H-phenoxazin-3-one
  参考文献：
  名称：

  A “Turn-on” Fluorescent Hg²⁺ Chemosensor Based on Ferrier Carbocyclization

  摘要：

  A "turn-on" fluorescent chemosensor with excellent selectivity and satisfactory sensitivity on Hg2+ detection in 100% water media has been established employing a carbohydrate based Ferrier carbocyclization reaction. The probe has also presented satisfactory results for the imaging of Hg2+ ions in cells and organisms.

  DOI：

  10.1021/ol2033477