4-bromo-1,2-dimethyl-1H-imidazole-5-carbaldehyde | 1246553-44-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-bromo-1,2-dimethyl-1H-imidazole-5-carbaldehyde
• 英文别名: 1H-Imidazole-5-carboxaldehyde, 4-bromo-1,2-dimethyl-；5-bromo-2,3-dimethylimidazole-4-carbaldehyde
• CAS: 1246553-44-5
• 化学式: C₆H₇BrN₂O
• 分子量: 203.038
• InChiKey: PVMMXAVLLYDYCU-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  甲基溴化镁 、 4-bromo-1,2-dimethyl-1H-imidazole-5-carbaldehyde 以 四氢呋喃 为溶剂， 以5.5 g的产率得到1-(4-bromo-1,2-dimethyl-1H-imidazol-5-yl)ethan-1-ol
  参考文献：
  名称：

  [EN] TYK2 INHIBITORS AND USES THEREOF
  [FR] INHIBITEURS DE TYK2 ET LEURS UTILISATIONS

  摘要：

  Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity. Formula (I):

  公开号：

  WO2023227946A1
• 作为产物：
  描述：

  4,5-二溴-1,2-二甲基-1H-咪唑 、 N,N-二甲基甲酰胺 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以5 g的产率得到4-bromo-1,2-dimethyl-1H-imidazole-5-carbaldehyde
  参考文献：
  名称：

  [EN] TYK2 INHIBITORS AND USES THEREOF
  [FR] INHIBITEURS DE TYK2 ET LEURS UTILISATIONS

  摘要：

  Described herein are compounds that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity. Formula (I):

  公开号：

  WO2023227946A1