| 1403877-03-1

• CAS: 1403877-03-1
• 化学式: C₂₈H₃₀Cl₂N₄O₂Zn
• 分子量: 590.868
• InChiKey: CLARQBPMUQVZBC-GGVBBUNRSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  、 zinc(II) chloride 以 乙醇 为溶剂， 反应 2.0h， 以70.58%的产率得到
  参考文献：
  名称：

  Nucleolytic Property Promoted by Biologically Active Metal-Based Complexes Formed by Neutral Quatridentate Ligands: Synthesis, Characterization, and DNA Binding Studies

  摘要：

  A series of Ni(II), Cu(II), and Zn(II) complexes have been synthesized and characterized with physicochemical and spectral techniques. Absorption titration study of the interaction of the complexes with calf-thymus (CT) DNA has shown that the complexes can bind to CT DNA. The cyclic voltammograms of all the complexes recorded in the presence of CT DNA-buffer solution have shown that they can bind to CT DNA via intercalation mode, which has also been verified by the viscosity experiments. The antimicrobial and DNA cleavage activities of all the compounds have also been investigated.

  DOI：

  10.1080/15533174.2012.684262