methyl 6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-O-methanesulphonyl-1-thio-2,3,4-tris-O-trimethylsilyl-α-lincosamide | 1088411-18-0
中文名称
——
中文别名
——
英文名称
methyl 6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-O-methanesulphonyl-1-thio-2,3,4-tris-O-trimethylsilyl-α-lincosamide
英文别名
methyl 6-N-((2S,4R)-1-tert-butoxycarbonyl-4-cyclopropylmethyl-pipecoloyl)-7-O-methanesulfonyl-1-thio-2,3,4-tri-O-trimethylsilyl-α-lincosamide
CAS
1088411-18-0
化学式
C34H68N2O10S2Si3
mdl
——
分子量
813.31
InChiKey
IRYACPHJVBQIDR-VAWIVMKPSA-N
BEILSTEIN
——
EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
计算性质
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辛醇/水分配系数(LogP)：6.4
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重原子数：51.0
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可旋转键数：15.0
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环数：3.0
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sp3杂化的碳原子比例：0.94
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拓扑面积：138.93
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氢给体数：1.0
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氢受体数：11.0
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— methyl 6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-1-thio-2,3,4-tris-O-trimethylsilyl-α-lincosamide 1088411-15-7 C33H66N2O8SSi3 735.218 —— methyl 6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-1-thio-α-lincosamide 1088411-16-8 C24H42N2O8S 518.672 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— methyl 7-acetylthio-6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-deoxy-7-epi-1-thio-2,3,4-tris-O-trimethylsilyl-α-lincosamide 1088411-19-1 C35H68N2O8S2Si3 793.322 —— methyl 6-N-((2S,4R)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-deoxy-7-epi-7-mercapto-1-thio-α-lincosamide 1088411-20-4 C24H42N2O7S2 534.739 —— methyl 7-acetylthio-6-N-((2S,4S)-1-(tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-deoxy-7-epi-1-thio-α-lincosamide 1089132-34-2 C26H44N2O8S2 576.776 —— methyl 6-N-((2S,4R)-1-(N-tert-butoxycarbonyl)-4-(cyclopropylmethyl)piperidine-2-carbonyl)-7-deoxy-7-epi-7-(4-(pyrrolidin-1-ylmethyl)phenylthio)-1-thio-α-lincosamide 1089132-47-7 C35H55N3O7S2 693.97 —— methyl 6-N-(((2S,4R)-1-tert-butoxycarbonyl-4-cyclopropylmethyl-pipecoloyl)7-deoxy-7-epi-7-(4-(pyrimidin-5-yl)pheny)thio)-1-thio-α-lincosamide 1088411-35-1 C34H48N4O7S2 688.91 —— methyl 6-N-((2S,4R)-1-tert-butoxycarbonyl-4-cyclopropylmethyl-pipecolyl)-7-deoxy-7-epi-7-(4-(1-methylpiperidin-3-yl)phenylthio)-1-thio-α-lincosamide 1088411-23-7 C36H57N3O7S2 707.996 —— methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-methylpipecoloyl)-7-deoxy-7-epi-7-(4-(pyridin-3-yl)phenylthio)-1-thio-α-lincosamide 1088409-60-2 C31H43N3O5S2 601.832 —— methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-methylpipecoloyl)-7-deoxy-7-epi-7-(4-(pyrazin-2-yl)phenylthio)-1-thio-α-lincosamide 1088409-97-5 C30H42N4O5S2 602.819 —— methyl (7S)-6-N-((2′S,4′R)-4′-(cyclopropylmethyl)-1′-N-methylpiperidine-2′-carbonyl)-7-deoxy-7-(4-(pyrimidin-5-yl)phenylthio)-α-thiolincosaminide 1088409-52-2 C30H42N4O5S2 602.819 —— methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-methylpiperidine-2-carbonyl)-7-deoxy-7-epi-7-(4-(pyrrolidin-1-ylmethyl)phenylthio)-1-thio-α-lincosamide 1089128-71-1 C31H49N3O5S2 607.879 —— methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-methylpipecoloyl)-7-deoxy-7-epi-7-(4-(1-methylpiperidin-3-yl)phenylthio)-1-thio-α-lincosamide 1088410-20-1 C32H51N3O5S2 621.906 —— methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-methylpipecoloyl)-7-deoxy-7-epi-7-(4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)phenylthio)-1-thio-α-lincosamide 1088410-13-2 C32H49N3O5S2 619.89