[(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2,2-dicyano-1-methylsulfanylethenyl)sulfanyloxan-2-yl]methyl acetate | 1167429-85-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2,2-dicyano-1-methylsulfanylethenyl)sulfanyloxan-2-yl]methyl acetate
• CAS: 1167429-85-7
• 化学式: C₁₉H₂₂N₂O₉S₂
• 分子量: 486.524
• InChiKey: JUHDUQZOEAPBDK-SFFUCWETSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  32
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  213
• 氢给体数：
  0
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  sodium (2,2-dicyano-1-methylthioethen-1-yl)thiolate 、 2,3,4,6-四乙酰氧基-alpha-D-吡喃葡萄糖溴化物 以 乙醇 、 丙酮 为溶剂， 反应 15.0h， 生成 [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2,2-dicyano-1-methylsulfanylethenyl)sulfanyloxan-2-yl]methyl acetate
  参考文献：
  名称：

  Design and Synthesis of the First Thiophene Thioglycosides

  摘要：

  A novel reported method for preparation of the first thiophene thioglycosides via a one-pot reaction of sodium thiophenethiolate salts with 2,3,4,6-tetra-O-acetyl--D-gluco- and galactopyranosyl bromides has been studied. The sodium thiophenethiolate salts were prepared using sodium cyanoethylene thiolate salts.

  DOI：

  10.1080/00397910802590928

文献信息

• Design and Synthesis of the First Thiophene Thioglycosides
  作者：Galal H. Elgemeie、Shahinaz H. Elsayed、Ashraf S. Hassan

  DOI：10.1080/00397910802590928

  日期：2009.4.22

  A novel reported method for preparation of the first thiophene thioglycosides via a one-pot reaction of sodium thiophenethiolate salts with 2,3,4,6-tetra-O-acetyl--D-gluco- and galactopyranosyl bromides has been studied. The sodium thiophenethiolate salts were prepared using sodium cyanoethylene thiolate salts.