2-hydroxy-3-[(Z)-3-(4-hydroxyphenyl)prop-2-enoyl]oxybutanedioic acid | 67920-37-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 2-hydroxy-3-[(Z)-3-(4-hydroxyphenyl)prop-2-enoyl]oxybutanedioic acid
• CAS: 67920-37-0
• 化学式: C₁₃H₁₂O₈
• 分子量: 296.23
• InChiKey: INYJZRKTYXTZHP-UTCJRWHESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  141
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Methods and compositions for applying essential oils and naturally occurring compounds to plants to activate endogenous plant pathogen defense pathways
  申请人：——

  公开号：US20030064119A1

  公开（公告）日：2003-04-03

  Compositions and methods are provided for activation of endogenous plant pathogen resistance pathways, including systemic acquired resistance, the hypersensitive reaction response and the upregulation of pathogenesis related proteins. The compositions comprise as active agents one or more naturally occurring compounds or essential oils selected from cedar oil, cinnamon oil, grapefruit oil, grapefruit seed extract oil, ferulic acid and acetyl salicylic acid. The methods involve directly applying formulations comprising one or more of these active agents to a Gymnosperm to induce endogenous plant defense pathways as a therapeutic or prophylactic treatment against fungal pathogens such as pitch canker and white pine blister rust.

  本发明提供了激活内源植物病原体抵抗途径的组合物和方法，包括系统获得性抗性、过敏反应和病原相关蛋白的上调。该组合物包括作为活性剂的一种或多种天然化合物或精油，包括雪松油、肉桂油、葡萄柚油、葡萄柚籽提取物油、阿魏酸和乙酰水杨酸。该方法涉及直接应用包含其中一种或多种活性剂的制剂，以诱导裸子植物内源植物防御途径，作为治疗或预防治疗针孔松树疫病和白松锈病等真菌病原体的方法。
• Glycan therapeutics and related methods thereof
  申请人：KALEIDO BIOSCIENCES, INC.

  公开号：US10314853B2

  公开（公告）日：2019-06-11

  Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

  本发明提供了可选择包含微量营养素、多酚、益生元、益生菌或其他制剂的聚糖疗法制剂、药物组合物及其医用食品，以及制造方法。还提供了使用所述糖治疗剂的方法，例如用于调节人类胃肠道微生物群和治疗菌群失调。
• Glycan therapeutics and method of treating conditions associated with TMAO
  申请人：Kaleido Biosciences, Inc.

  公开号：US11229660B2

  公开（公告）日：2022-01-25

  Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

  本发明提供了可选择包含微量营养素、多酚、益生元、益生菌或其他制剂的聚糖疗法制剂、药物组合物及其医用食品，以及制造方法。还提供了使用所述糖治疗剂的方法，例如用于调节人类胃肠道微生物群和治疗菌群失调。
• GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3071235A1

  公开（公告）日：2016-09-28
• GLYCAN COMPOSITIONS AND USES THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3334437A1

  公开（公告）日：2018-06-20