Quinolin-8-ol hydrate | 195244-65-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: Quinolin-8-ol hydrate
• 英文别名: quinolin-8-ol;hydrate
• CAS: 195244-65-6
• 化学式: C9H9NO2
• 分子量: 163.17
• InChiKey: YMSUVRRJENNWNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.12
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  34.1
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• O-AMINOMETHYLPHENOL COMPOUNDS
  申请人：Yoshitomi Pharmaceutical Industries, Ltd.

  公开号：EP0191108A1

  公开（公告）日：1986-08-20

  o-Aminomethylphenol compounds represented by general formula (I), (wherein X represents hydrogen or halogen, R represents hydrogen or C1-4 alkyl, A represents C1-4 alkyl, phenyl, benzyl or a bifunctional chain of -(CH2)3-or -O(CH2)2-bound to position 3 or 5 of the benzene nucleus to form a bicyclic system) or pharmaceutically acceptable salts thereof, a process for their preparation, and a pharmaceutical composition containing them. The compounds have antiinflammatory, analgesic, diuretic, and hypotensive effects, and are useful for treating diseases due to inflammation, edema, hypertension, etc.

  o-Aminomethylphenol compounds represented by general formula (I), (wherein X represents hydrogen or halogen, R represents hydrogen or C1-4 alkyl, A represents C1-4 alkyl, phenyl, benzyl or a bifunctional chain of -(CH2)3-or -O( )2-bound to position 3 or 5 of the benzene nucleus to form a bicyclic system) or pharmaceutically acceptable salts of thereof, a process for their preparation, and a pharmaceutical composition containing them. 这些化合物具有抗炎、镇痛、利尿和降压作用，可用于治疗炎症、水肿、高血压等疾病。
• ERYTHROMYCIN A OXIME SOLVATES
  申请人：Biochemie S.A.

  公开号：EP0994889B1

  公开（公告）日：2004-06-16
• NOUVELLES UTILISATIONS D'UNE LACTONASE MUTEE ET COMPOSITIONS
  申请人：Fondation Méditerranée Infection

  公开号：EP3941206A1

  公开（公告）日：2022-01-26
• US4128425A
  申请人：——

  公开号：US4128425A

  公开（公告）日：1978-12-05
• US4730006A
  申请人：——

  公开号：US4730006A

  公开（公告）日：1988-03-08