1,5-dicyclopentyl-pentan-3-one | 55317-35-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,5-dicyclopentyl-pentan-3-one
• 英文别名: 1,5-Dicyclopentyl-pentan-3-on；1,5-dicyclopentylpentan-3-one
• CAS: 55317-35-6
• 化学式: C₁₅H₂₆O
• 分子量: 222.371
• InChiKey: KLJLEZCKUXZXAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,3'-二氨基二丙基胺 、 1,5-dicyclopentyl-pentan-3-one 生成 [3-(3-Amino-propylamino)-propyl]-[3-cyclopentyl-1-(2-cyclopentyl-ethyl)-propyl]-amine
  参考文献：
  名称：

  Antibacterial N-[.omega.,.omega.'-bis(alicyclic and aryl)-sec-alkyl]poly(methylenetriamine and -tetramine) hydrochloride salts

  摘要：

  A series of antibacterial N-(omega, omega'-(cycloalkyl, bicyclo[2.2.1]heptyl, and alkyl-substituted phenyl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts were synthesized in an effort to develop efficient, nonsystemic inhibitors, particularly for Pseudomonas aeruginosa. In the 1,5,9-triazanonane group, 3 of 16 compounds were effective at 8--10 micrograms/mL against pseudomonads. Efficiency appeared more dependent upon lipophilicity of the nitrogen substituent than other characteristics represented by the three types of rings. A parabolic relationship was observed for the entire set between the hydrophobic parameter, pi, of the lipoidal moiety and minimal inhibitory concentration. One of 16 tetramines, 1-[1,5-bis(3,3-dimethyl-2-norbornyl)-3-pentyl]-1,5,9,13-tetraazatridecane tetrahydrochloride (26f), ranked similarly. An additional two compounds in each series were superior to several commercial cationic detergents in the control of the Gram-negative bacteria. None was inhibitory at up to 200 micrograms/mL for Proteus vulgaris.

  DOI：

  10.1021/jm00197a024
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 铜 作用下， 生成 1,5-dicyclopentyl-pentan-3-one
  参考文献：
  名称：

  225.简单脂族酮的二环衍生物

  摘要：

  DOI：

  10.1039/jr9350000982