(2R,3R,4S,5S,6R)-6-Hydroxymethyl-3-tetradecyloxy-tetrahydro-pyran-2,4,5-triol | 142025-90-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4S,5S,6R)-6-Hydroxymethyl-3-tetradecyloxy-tetrahydro-pyran-2,4,5-triol
• 英文别名: (2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3-tetradecoxyoxane-2,4,5-triol
• CAS: 142025-90-9
• 化学式: C₂₀H₄₀O₆
• 分子量: 376.534
• InChiKey: YLBUIXJXVBDIME-OUUBHVDSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Stable non-aqueous pharmaceutical compositions
  申请人：Novo Nordisk A/S

  公开号：EP2514407A1

  公开（公告）日：2012-10-24

  The present invention relates to shelf stable non-aqueous pharmaceutical compositions comprising a dehydrated therapeutically active polypeptide comprising 10-100 amino acids, at least one semi-polar protic organic solvent and which polypetide has been dehydrated at a target pH which is at least 1 pH unit distant from the pI. The composition can be used in methods of treating diabetes, hyperglycaemia and impaired glucose tolerance.

  本发明涉及货架稳定的非水性药物组合物，该组合物包含脱水的具有治疗活性的多肽，该多肽包含 10-100 个氨基酸、至少一种半极性质子有机溶剂，并且该多肽已在目标 pH 值下脱水，该 pH 值与 pI 值相差至少 1 个 pH 单位。该组合物可用于治疗糖尿病、高血糖和糖耐量受损的方法。
• PNEUMATIC TIRE
  申请人：Sumitomo Rubber Industries, Ltd.

  公开号：EP3495162A1

  公开（公告）日：2019-06-12

  Provided is a pneumatic tire having steel breaker topping rubber that allows fuel economy, steering stability, and durability to be improved in a well-balanced manner. A pneumatic tire has steel breaker topping rubber produced by using a rubber composition in which rubber physical properties satisfy a specific value after vulcanization.

  本实用新型提供了一种充气轮胎，该轮胎具有钢质断路器顶部橡胶，能够以平衡的方式提高燃油经济性、转向稳定性和耐用性。 该充气轮胎采用橡胶组合物，在硫化后，橡胶物理性能满足特定值，从而生产出具有钢质断路器顶胶的充气轮胎。
• METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS
  申请人：THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

  公开号：EP1814559A1

  公开（公告）日：2007-08-08
• Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis
  申请人：Sostaric Joe Z.

  公开号：US20080269163A1

  公开（公告）日：2008-10-30

  Described herein are methods for protecting cells from ultrasound-mediated cytolysis.
• [EN] METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS<br/>[FR] METHODES ET COMPOSITIONS DE PROTECTION DE CELLULES DE LA CYTOLYSE A MEDIATION ULTRASONORE
  申请人：REPRESENTED BY THE SECRETARY D

  公开号：WO2006045050A1

  公开（公告）日：2006-04-27

  [EN] Described herein are methods for protecting cells from ultrasound-mediated cytolysis.
  [FR] L'invention concerne des méthodes de protection de cellules de la cytolyse à médiation ultrasonore.