diacetyl-trisulfane | 861297-44-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: diacetyl-trisulfane
• 英文别名: Diacetyl-trisulfan；Diacetyltrisulfid；S-(acetyldisulfanyl) ethanethioate
• CAS: 861297-44-1
• 化学式: C₄H₆O₂S₃
• 分子量: 182.288
• InChiKey: ICWVZQBZKABNJZ-UHFFFAOYSA-N

物化性质

• 熔点：
  -19--17 °C
• 沸点：
  297.6±23.0 °C(Predicted)
• 密度：
  1.3423 g/cm3(Temp: 22 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  110
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  diacetyl-trisulfane 在 四氯化碳 、 氯 作用下， 生成 acetyl-chloro-trisulfane
  参考文献：
  名称：

  Boehme; Zinner, Justus Liebigs Annalen der Chemie, 1954, vol. 585, p. 142,146

  摘要：

  DOI：
• 作为产物：
  描述：

  乙酰氯 在 hydro trisulfide 、 zinc(II) chloride 作用下， 生成 diacetyl-trisulfane
  参考文献：
  名称：

  Removal of the connector on the laryngeal mask airway provides a useful alternative to the intubating laryngeal mask

  摘要：

  Purpose: We describe two cases in which fiberoptic intubation through the standard laryngeal mask airway (LMA) was successful with large-bore tracheal tubes (TTs) when an intubating LMA (ILMA) could not be used.Clinical features: Patient #, with obstructive sleep apnea, underwent elective surgical repair. His mouth opening was just under 25 mm, but difficult intubation was not anticipated. We induced general anesthesia, easily ventilated the patient by mask, and established neuromuscular blockade. Direct laryngoscopy and attempts to insert either a #5 or a #4 ILMA into the mouth failed. A standard #4 LMA, with the connector removed, was inserted, through which a 7.0 mm nasal RAE (TM) TT; fiberoptically guided, passed into the trachea at the first attempt. Patient #2, with a loosened implant after left hip arthroplasty, underwent revision prosthesis. Her neck movement was limited. We thus planned awake securing of the airway, but the patient refused. We induced anesthesia and established bag-mask-valve ventilation. The limited neck movement prevented direct laryngoscopy. Visualizing the laryngeal inlet with the fiberoptic bronchoscope (FOB) proved impossible as bloody secretions obscured the FOB's tip. Ventilation by mask was easy. As an ILMA was not available, we removed a #5 LMA's connector and passed an 8.0 mm nasal RAE (TM) TT through the LMA. fiberoptic-guided intubation was easy, In both cases, the remainder of the intraoperative course was uneventful.Conclusion: A standard LMA whose connector has been removed to allow passage of TTs of >6.0 mm internal diameter may be substituted for the ILMA when necessary.

  DOI：

  10.1007/bf03016839

文献信息

• Nucleophilic substitution of acyl chlorides by electrogenerated polysulfide ions in N,N-dimethylacetamide
  作者：Julie Robert、Meriem Anouti、Mohamed Abarbri、Jacky Paris

  DOI：10.1039/a700939i

  日期：——

  The reactions between acyl chlorides RC(O)Cl (a) [R = Me (1), Pri (2), But (3), Ph(4)] and electrogenerated S3˙- (⇌ S62- ) ions have been investigated in N,N-dimethylacetamide by spectroelectrochemistry. With R = alkyl, thiocarboxylate ions and sulfur resulting from the fast initial substitutions cause partial formation of both acyl disulfide ions and diacyl disulfides (b) at a y ratio [RC(O)Cl]/[S3˙-] of 0.5; the second step stoichiometrically (y = 1) affords diacyl disulfides 1b–4b as the presumed products. The formation of these species only is confirmed on a preparative scale from two sets of experiments: (i) direction addition of acyl chlorides (1a–4a) to chemically generated S⅓- solutions; (ii) electrolysis of sulfur in the presence of acyl chlorides 2a–4a.

  已经通过光谱电化学方法研究了酰氯 RC(O)Cl (a) [R = Me (1), Pri (2), But (3), Ph (4)] 与电生S3˙- (⇌ S62-) 离子在N,N-二甲基乙酰胺中的反应。当R为烷基时，迅速的初始取代反应产生的硫代羧酸盐离子和硫导致在[RC(O)Cl]/[S3˙-]的比率为0.5时部分生成酰二硫酸盐离子和二酰二硫化物 (b)；第二步化学计量（y = 1）生成二酰二硫化物1b–4b作为假定产物。通过两组实验的备制结果确认了这些物质的形成：(i) 将酰氯 (1a–4a) 直接添加到化学生成的S⅓-溶液中；(ii) 在酰氯2a–4a存在下电解硫。