(E)-1-propenyl-N,N,N',N'-tetraisopropylphosphonodiamide | 1145788-15-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: (E)-1-propenyl-N,N,N',N'-tetraisopropylphosphonodiamide
• CAS: 1145788-15-3
• 化学式: C₁₅H₃₃N₂OP
• 分子量: 288.414
• InChiKey: KZINQWSVPIOITM-ZHACJKMWSA-N

物化性质

• 熔点：
  83-86 °C(Solvent: Pentane)
• 沸点：
  340.8±25.0 °C(predicted)
• 密度：
  0.930±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  N-[[di(propan-2-yl)amino]-[(2S,3S)-3-methyl-2-trimethylsilyloxiran-2-yl]phosphanyl]-N-propan-2-ylpropan-2-amine 在 双(三甲基硅基)过氧化物 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 0.5h， 生成 (E)-1-propenyl-N,N,N',N'-tetraisopropylphosphonodiamide
  参考文献：
  名称：

  A stereoselective synthetic entry to β-substituted α-[(trans)-vinyl] phosphonamides

  摘要：

  alpha-(trans-Vinyl) phosphonamides with different substituents at the beta-position were stereoselectively synthesized in high yields by treatment of beta-substituted alpha-epoxy-alpha-trimethylsilyl phosphines with oxidizing agents. The corresponding phosphonamides were unstable in most cases and underwent reductive elimination affording desilylated vinyl derivatives. In turn, alpha-epoxy phosphines resulted from the [1 + 2] addition of [bis(diisopropylamino)phosphino](trimethylsilyl)carbene 2 to aliphatic, aromatic, and heteroaromatic aldehydes. In this way, a great variety of vinyl Compounds have been efficiently prepared through one-pot procedure. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.01.074