(1R,3R)-cyclohexane-1,3-diyldimethanol | 13022-98-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1R,3R)-cyclohexane-1,3-diyldimethanol
• 英文别名: trans-1,3-cyclohexanedimethaneol；trans-1,3-cyclohexanedimethanol；trans-1,3-Cyclohexandimethanol；[(1S,3S)-3-(hydroxymethyl)cyclohexyl]methanol
• CAS: 13022-98-5
• 化学式: C₈H₁₆O₂
• 分子量: 144.214
• InChiKey: LUSFFPXRDZKBMF-YUMQZZPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (1R,3R)-cyclohexane-1,3-diyldimethanol 、 甲基磺酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 生成 [(1S,3S)-3-(methylsulfonyloxymethyl)cyclohexyl]methyl methanesulfonate
  参考文献：
  名称：

  [EN] GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE
  [FR] INHIBITEURS DE GLYCOLATE OXYDASE POUR LE TRAITEMENT D'UNE MALADIE

  摘要：

  本文描述了化合物、制备这种化合物的方法、含有这种化合物的药物组合物和药物，以及使用这种化合物治疗或预防与甘氧酸代谢缺陷相关的疾病或紊乱的方法，例如与甘氧酸氧化酶（GO）或草酸代谢变化相关的疾病或紊乱。这些疾病或紊乱包括与产生过多草酸相关的甘氧酸代谢紊乱，例如原发性高草酸尿症。

  公开号：

  WO2020257487A1

文献信息

• Liquid-crystal polyester resin
  申请人：Ueno Ryuzo

  公开号：US20050054811A1

  公开（公告）日：2005-03-10

  The present invention provides a liquid-crystalline polyester resin which comprises monomer units derived from 2-hydroxy-3-naphthoic acid and/or 2-hydroxynaphthalene-3,6-dicarboxylic acid in an amount of 1-5000 mmol % based on the total monomer components of the resin and an alkaline metal compound in an amount of 10-3000 ppm as alkaline metal based on the total monomer components of the resin. The liquid-crystalline polyester resin of the present invention has good colorability, improved heat resistance and good mechanical properties.

  本发明提供了一种液晶聚酯树脂，其包含从2-羟基-3-萘甲酸和/或2-羟基萘并[3,6-二羧酸]衍生的单体单位，其数量为树脂总单体组分的1-5000 mmol％，以及一种碱性金属化合物，其数量为树脂总单体组分的10-3000 ppm作为碱性金属。本发明的液晶聚酯树脂具有良好的着色性，改善的耐热性和良好的机械性能。
• HIGH STRENGTH DENTAL MATERIAL
  申请人：SUN BENJAMIN J.

  公开号：US20120129973A1

  公开（公告）日：2012-05-24

  The invention provides a high strength dental composition including polymerizable dental resins. The dental composition is useful as restorative material and for making various dental devices, such as artificial teeth, crowns and bridges of high strength dental polymeric material.

  本发明提供了一种高强度的牙科组合物，包括可聚合的牙科树脂。该牙科组合物可用作修复材料，并用于制造各种高强度牙科聚合材料的人工牙齿，冠和桥。
• THERMOPLASTIC RESIN WITH HIGH THERMAL CONDUCTIVITY
  申请人：Yoshihara Shusuke

  公开号：US20130035468A1

  公开（公告）日：2013-02-07

  Provided is a thermoplastic resin having excellent thermal conductivity, in which thermoplastic resin a change in number average molecular mass caused by progress of polymerization occurring when the thermoplastic resin material is melted and a change in thermal conductivity caused by the change in number average molecular mass are low. The thermoplastic resin has (A) a specific structure and (B) ends of molecular chains sealed by a monofunctional low molecular weight compound. The resin itself has excellent thermal conductivity. The change in number average molecular mass becomes small during melting of the thermoplastic resin material, so that the change in thermal conductivity of the resin itself becomes small.

  提供的是一种具有优异热导率的热塑性树脂，其中该热塑性树脂具有（A）特定结构和（B）由单官能低分子量化合物密封的分子链末端。当热塑性树脂材料熔化时，由聚合进展引起的数量平均分子量变化以及由数量平均分子量变化引起的热导率变化都很小。该树脂本身具有优异的热导率。在热塑性树脂材料熔化过程中，数量平均分子量的变化变得很小，因此树脂本身的热导率变化也很小。
• ADVANCED POLY EPOXY ESTER RESIN COMPOSITIONS
  申请人：Jin Xin

  公开号：US20130178591A1

  公开（公告）日：2013-07-11

  A poly epoxy ester resin composition of the following chemical structure: where n is a number from 2 to about 3000; each m independently has a value of 0 or 1; each R 0 is independently —H or —CH 3 ; each R 1 is independently —H or a C 1 to C 6 alkylene radical (saturated divalent aliphatic hydrocarbon radical), Ar is a divalent aryl group or heteroarylene group;_and X is cycloalkylene group, including substituted cycloalkylene group, where the substitute group include an alkyl, cycloalkyl, an aryl or an aralkyl group or other substitute group, for example, a halogen, a nitro, a blocked isocyanate, or an alkyloxy group; the combination of cycloalkylene and alkylene groups and the combination of alkylene and cycloalkylene group with a bridging moiety in between.

  以下是化学结构式为的聚合物环氧酯树脂组成：其中n为2至约3000的数字；每个m独立地具有值为0或1；每个R0独立地为—H或—CH3；每个R1独立地为—H或C1到C6的烷基基团（饱和二价脂肪族碳氢基团），Ar为二价芳基基团或杂芳基基团；X为环烷基团，包括取代环烷基团，其中取代基团包括烷基、环烷基、芳基或芳基烷基团或其他取代基团，例如卤素、硝基、阻塞异氰酸酯或烷氧基团；环烷基和烷基团的组合以及烷基和环烷基团之间带有桥接基团。
• Process for producing electroconductive resin composite
  申请人：POLYPLASTICS CO. LTD.

  公开号：EP0184367A1

  公开（公告）日：1986-06-11

  An electroconductive resin composite is produced by polymerizing at least one monomer a polymer of which is electroconductive in a matrix of a resin which exhibits the anisotropy in the melt phase to form a composite of the obtained polymer and the resin. The resin composite is obtained in the form of film and a moulded article.

  一种导电树脂复合材料是通过将至少一种单体聚合在一种树脂基体中制成的，这种树脂基体具有导电性，在熔融相中表现出各向异性，从而形成所获得的聚合物和树脂的复合材料。这种树脂复合材料可以薄膜和模制件的形式获得。