2-[(4-Methoxyphenyl)methylidene]-3-methylbutanoic acid | 899828-72-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 2-[(4-Methoxyphenyl)methylidene]-3-methylbutanoic acid
• CAS: 899828-72-9
• 化学式: C₁₃H₁₆O₃
• 分子量: 220.26
• InChiKey: WWMRWVQZJZYDOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COSMETIC
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20200281836A1

  公开（公告）日：2020-09-10

  A cosmetic containing (A) an organo(poly)siloxane shown by the following general formula (1). A cosmetic with a refreshing feeling, smooth spreadability as well as high stability and favorable cosmetic sustainability is provided. [where, in the formula, R 1 represents a group except shown by the formula (2), selected from a C1-C20 alkyl group and a C6-C20 aryl group; n represents an integer of 0 to 3; R 2 and R 3 represent R 1 or the formula (2); and either or both of R 2 and R 3 represent formula (2), (where, in the formula, X represents a C2-C20 alkylene group; and Y represents any one of a hydrogen atom, a C1-C20 alkyl group, a C6-C20 aryl group, a C7-C40 aralkyl group, a C1-C20 alkyloxy group, a C6-C20 aryloxy group, a C7-C40 arylalkyloxy group, and a halogen atom.)]

  一种化妆品，含有以下一般式（1）所示的有机（聚）硅氧烷。提供一种具有清爽感、平滑涂抹性以及高稳定性和良好的化妆品持久性的化妆品。【在公式中，R1代表除公式（2）所示之外的一种基团，选自C1-C20烷基基团和C6-C20芳基基团；n代表0到3之间的整数；R2和R3代表R1或公式（2）；R2和R3中的任一或两者代表公式（2），（在公式中，X代表C2-C20烷基基团；Y代表氢原子、C1-C20烷基基团、C6-C20芳基基团、C7-C40芳基烷基基团、C1-C20烷氧基团、C6-C20芳氧基团、C7-C40芳基烷氧基团和卤素原子中的任意一种。）】
• Solid Wax Composition and Solid Oily Cosmetic
  申请人：The Nisshin OilliO Group, Ltd.

  公开号：US20190307672A1

  公开（公告）日：2019-10-10

  The present invention provides a composition that has an excellent hardness adjustment action, can be used as a solidifying agent for various cosmetics, and when added to cosmetics, can impart those cosmetics with excellent shape retention properties, an oil oozing suppression effect during use, a favorable texture and good storage stability, and also provides an oily solid cosmetic to which the composition has been added. Specifically, the invention provides a solid wax composition containing a component (A):candelilla wax, and a component (B): a monoester having a total of 40 to 48 carbon atoms, wherein the mass ratio between the component (A) and the component (B) in the solid wax composition satisfies component (A):component (B)=45:55 to 95:5, and the monoester is a monoester of a monovalent fatty acid and a monohydric alcohol.

  本发明提供了一种具有优异硬度调节作用的组合物，可用作各种化妆品的固化剂，并且当添加到化妆品中时，可以赋予这些化妆品优秀的保持形状性能、使用过程中的抑制油分泌效果、良好的质地和良好的储存稳定性，并且提供了添加了该组合物的油性固体化妆品。具体来说，该发明提供了一种固体蜡组合物，包含组分（A）：蜡燭树蜡，以及组分（B）：总碳原子数为40至48的单酯，其中在固体蜡组合物中，组分（A）和组分（B）之间的质量比满足组分（A）：组分（B）=45:55至95:5，而且该单酯是一种单价脂肪酸和一价醇的单酯。
• STICK-SHAPED BASE MATERIAL COMPRISING LIPID PEPTIDE COMPOUND
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20180200173A1

  公开（公告）日：2018-07-19

  A solid base material for external use on skin that has a breaking strength sufficiently high to be usable as a stick-shaped base material or the like. A solid base material for external use on skin containing a lipid peptide compound including at least one of compound of Formula (1), the similar compound thereof and the pharmacologically usable salts thereof; water; and a 1,3-alkanediol; wherein R 1 is a C 9-23 aliphatic group; R 2 is a hydrogen atom or a C 1-4 alkyl group optionally having a C 1 or C 2 branched chain; and R 3 is a —(CH 2 ) n —X group, wherein n is a number from 1 to 4, and X is amino group, guanidino group, -CONH 2 group, or a 5-membered ring group or 6-membered ring group optionally having one to three nitrogen atoms or a fused heterocyclic group composed of the 5-membered ring and the 6-membered ring.

  一种用于外用于皮肤的固体基材料，其断裂强度足够高，可用作棒状基材料或类似物。一种用于外用于皮肤的固体基材料，包含一个脂肽化合物，其中至少包括公式（1）的化合物、类似的化合物及其药学可用的盐；水；和1,3-烷二醇；其中R1是C9-23脂肪基；R2是氢原子或C1-4烷基，可选地具有C1或C2支链；R3是—（CH2）n—X基团，其中n是1至4之间的数字，而X是氨基、鸟氨酸基、-CONH2基团或具有1至3个氮原子或由5-成员环和6-成员环组成的融合杂环基团中的5-成员环基团或6-成员环基团。
• STICK-SHAPED BASE MATERIAL HAVING HIGH WATER CONTENT
  申请人：NISSAN CHEMICAL CORPORATION

  公开号：US20200197284A1

  公开（公告）日：2020-06-25

  A stick-shaped base material capable of having a breaking strength required for a stick-shaped base material even when the amount of a lipid peptide compound contained therein is reduced, including: a surfactant; water; a lipid peptide compound including at least one of compound of the following Formula (1) and similar compound thereof or pharmaceutically usable salts of the compounds: wherein R 1 is a C 9-23 aliphatic group; R 2 is a hydrogen atom or a C 1-4 alkyl group optionally having a C 1 or C 2 branched chain; and R 3 is a —(CH 2 ) n —X group, wherein n is a number of 1 to 4, and X is an amino group, guanidine group, or a —CONH 2 group, or a 5-membered or 6-membered ring optionally having one to three nitrogen atoms or a fused heterocyclic ring composed of the rings; a 1,2-alkanediol or a 1,3-alkanediol; at least one fatty acid; and an alginic acid derivative.

  一种棒状基材料，即使其中含有脂肽化合物的量减少，仍能具有棒状基材料所需的断裂强度，包括：表面活性剂；水；脂肽化合物，其中包括以下式（1）的化合物和类似化合物或其药用盐之一：其中R1是C9-23脂肪基；R2是氢原子或C1-4烷基，可选地具有C1或C2支链；R3是—（CH2）n—X基团，其中n为1至4的数字，X是氨基、鸟氨酸基或—CONH2基团，或者是具有1至3个氮原子的5元或6元环，或者是由这些环组成的融合杂环；1,2-癸二醇或1,3-癸二醇；至少一种脂肪酸；和藻酸衍生物。
• STICK-TYPE SOLID BASE MATERIAL FOR EXTERNAL APPLICATION TO SKIN
  申请人：NISSAN CHEMICAL CORPORATION

  公开号：US20200138679A1

  公开（公告）日：2020-05-07

  A solid base material is capable of preventing “sweating” over time. A stick-type solid base material for external application to skin including a lipidic peptide compound including at least one of compounds of the following Formulae (1), the similar compounds thereof or pharmaceutically usable salts of the compounds, a surfactant, water, an oily base, and a saturated or unsaturated monohydric alcohol having a carbon atom number of 8 to 30: wherein R 1 is a C 9-23 aliphatic group; R 2 is a hydrogen atom or a C 1-4 alkyl group optionally having a C 1 or C 2 branched chain; and R 3 is a —(CH 2 ) n —X group, n is a number of 1 to 4, and X is an amino group, a guanidino group, a —CONH 2 group, or a 5-membered ring or 6-membered ring optionally having one to three nitrogen atoms or a fused heterocyclic ring composed of the 5-membered ring and the 6-membered ring.

  一种固体基材料能够防止“出汗”现象。一种用于外部涂抹于皮肤的棒状固体基材料，包括脂肪肽化合物，其中至少包括以下化合物之一，其类似化合物或化合物的药用盐，表面活性剂，水，油性基质和具有8到30个碳原子数的饱和或不饱和单醇：其中R1是C9-23脂肪基；R2是氢原子或C1-4烷基，可选地具有C1或C2支链；R3是-（CH2）n-X基团，其中n是1到4的数字，X是氨基团，鸟氨酸基团，-CONH2基团，或具有1到3个氮原子的5元环或6元环，或由5元环和6元环组成的融合杂环。