1-[4-[[2-[(4-Prop-2-ynoylphenoxy)methyl]phenyl]methoxy]phenyl]prop-2-yn-1-one | 1413282-64-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-[4-[[2-[(4-Prop-2-ynoylphenoxy)methyl]phenyl]methoxy]phenyl]prop-2-yn-1-one
• CAS: 1413282-64-0
• 化学式: C₂₆H₁₈O₄
• 分子量: 394.427
• InChiKey: FDJRIHABFJHGTQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  间苯三酚 、 1-[4-[[2-[(4-Prop-2-ynoylphenoxy)methyl]phenyl]methoxy]phenyl]prop-2-yn-1-one 在 hexafluorophosphoric acid 、 溶剂黄146 作用下， 以 水 为溶剂， 反应 48.0h， 以99%的产率得到
  参考文献：
  名称：

  Four-Step Route to Novel Bisflavylium Dications - First Synthesis of Phloroglucinol-Type Derivatives

  摘要：

  Various bisflavylium dications have been prepared in an efficient four-step manner utilizing the acid-mediated condensation between bis(arylethynylketones) and activated phenols as the key step. Of special note is that phloroglucinol-type bisflavylium salts have been obtained for the first time thanks to this procedure.

  DOI：

  10.1055/s-0032-1316681
• 作为产物：
  描述：

  1,2-benzyloxy-bis-(4-benzaldehyde) 在 2-碘酰基苯甲酸 作用下， 以 四氢呋喃 、 乙酸乙酯 为溶剂， 反应 12.0h， 生成 1-[4-[[2-[(4-Prop-2-ynoylphenoxy)methyl]phenyl]methoxy]phenyl]prop-2-yn-1-one
  参考文献：
  名称：

  Four-Step Route to Novel Bisflavylium Dications - First Synthesis of Phloroglucinol-Type Derivatives

  摘要：

  Various bisflavylium dications have been prepared in an efficient four-step manner utilizing the acid-mediated condensation between bis(arylethynylketones) and activated phenols as the key step. Of special note is that phloroglucinol-type bisflavylium salts have been obtained for the first time thanks to this procedure.

  DOI：

  10.1055/s-0032-1316681

文献信息

• Four-Step Route to Novel Bisflavylium Dications - First Synthesis of Phloroglucinol-Type Derivatives
  作者：Marie Kueny-Stotz、Stefan Chassaing、Raymond Brouillard

  DOI：10.1055/s-0032-1316681

  日期：2012.9

  Various bisflavylium dications have been prepared in an efficient four-step manner utilizing the acid-mediated condensation between bis(arylethynylketones) and activated phenols as the key step. Of special note is that phloroglucinol-type bisflavylium salts have been obtained for the first time thanks to this procedure.