N-(tert-butyl)-1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-amine | 1070773-72-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: N-(tert-butyl)-1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-amine
• CAS: 1070773-72-6
• 化学式: C₂₀H₂₃NO
• 分子量: 293.409
• InChiKey: DCUXVDYALRIAKF-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  4-甲氧基苯甲醛 、 叔丁胺 、 苯基乙炔基三甲基硅烷 在 copper(II) bis(trifluoromethanesulfonate) 、 copper(l) chloride 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以16%的产率得到N-(tert-butyl)-1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-amine
  参考文献：
  名称：

  Facile and Selective Synthesis of Propargylic Amines and 1,6-Diynes: One-Pot Three-Component Coupling Reactions of Alkynylsilanes, Aldehydes and Amines by a Cooperative Catalytic System Comprised of CuCl and Cu(OTf)₂

  摘要：

  Described herein is a three-component coupling reaction of alkynylsilanes, aldehydes and amines by a cooperative catalytic system comprised of CuCl and Cu(OTf)(2), leading to the production of a variety of propargyl amine derivatives. This catalytic system was successfully applied to the practical preparation of 1,6-diyne derivatives via twice-performed, domino-type coupling reactions.

  DOI：

  10.1055/s-2008-1077790