2-[(Hexylcarbamoyl)amino]ethyl 2-methylprop-2-enoate | 117318-88-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(Hexylcarbamoyl)amino]ethyl 2-methylprop-2-enoate
• 英文别名: 2-(hexylcarbamoylamino)ethyl 2-methylprop-2-enoate
• CAS: 117318-88-4
• 化学式: C₁₃H₂₄N₂O₃
• 分子量: 256.34
• InChiKey: LHCBDXUUZALYCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  18
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-[(Hexylcarbamoyl)amino]ethyl 2-methylprop-2-enoate 在 四丁基氯化铵 作用下， 以 氘代二甲亚砜 为溶剂， 生成
  参考文献：
  名称：

  10.1002/anie.202408558

  摘要：

  Synthetic structures mimicking the transport function of natural ion channel proteins have a wide range of applications, including therapeutic treatments, separation membranes, sensing, and biotechnologies. However, the development of polymer‐based artificial channels has been hampered due to the limitation on available models. In this study, we demonstrate the great potential of bottlebrush polymers as accessible and versatile molecular scaffolds for developing efficient artificial ion channels. Adopting the bottlebrush configuration enhanced ion transport activity of the channels compared to their linear analogs. Matching the structure of lipid bilayers, the bottlebrush channel with a hydrophilic‐hydrophobic‐hydrophilic triblock architecture exhibited the highest activity among the series. Functionalized with urea groups, these channels displayed high anion selectivity. Additionally, we illustrated that the transport properties could be fine‐tuned by modifying the chemistry of ion binding sites. This work not only highlights the importance of polymer topology control in channel design, but also reveals the great potential for further developing bottlebrush channels with customized features and diverse functionalities.

  DOI：

  10.1002/anie.202408558
• 作为产物：
  描述：

  正己胺 、 甲基丙烯酸异氰基乙酯 以 四氢呋喃 为溶剂， 生成 2-[(Hexylcarbamoyl)amino]ethyl 2-methylprop-2-enoate
  参考文献：
  名称：

  10.1002/anie.202408558

  摘要：

  Synthetic structures mimicking the transport function of natural ion channel proteins have a wide range of applications, including therapeutic treatments, separation membranes, sensing, and biotechnologies. However, the development of polymer‐based artificial channels has been hampered due to the limitation on available models. In this study, we demonstrate the great potential of bottlebrush polymers as accessible and versatile molecular scaffolds for developing efficient artificial ion channels. Adopting the bottlebrush configuration enhanced ion transport activity of the channels compared to their linear analogs. Matching the structure of lipid bilayers, the bottlebrush channel with a hydrophilic‐hydrophobic‐hydrophilic triblock architecture exhibited the highest activity among the series. Functionalized with urea groups, these channels displayed high anion selectivity. Additionally, we illustrated that the transport properties could be fine‐tuned by modifying the chemistry of ion binding sites. This work not only highlights the importance of polymer topology control in channel design, but also reveals the great potential for further developing bottlebrush channels with customized features and diverse functionalities.

  DOI：

  10.1002/anie.202408558

文献信息

• PIGMENT DISPERSION COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR SOLID-STATE IMAGE SENSOR AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE SENSOR
  申请人：Kuge Toshihito

  公开号：US20120286145A1

  公开（公告）日：2012-11-15

  The invention provides a pigment dispersion composition including an azo pigment represented by formula (1), in which the azo pigment represented by formula (1) does not have an ionic hydrophilic group, an azo pigment derivative and a dispersant. In formula (1), G represents a hydrogen atom, an aliphatic group, an aryl group or a heterocyclic group; R 1 represents an amino group, an aliphatic oxy group, an aliphatic group, an aryl group or a heterocyclic group; R 2 represents a substituent; A represents a heterocyclic group; m represents an integer of 0 to 5; and n represents an integer of 1 to 4, wherein: when n=2, the azo pigment is a dimer formed via R 1 , R 2 , A or G; when n=3, the azo pigment is a a trimer formed via R 1 , R 2 , A or G; and when n=4, the azo pigment is a tetramer formed via R 1 , R 2 , A or G.

  本发明提供了一种颜料分散组合物，包括由公式（1）表示的偶氮颜料，其中由公式（1）表示的偶氮颜料不具有离子亲水基团，还包括偶氮颜料衍生物和分散剂。在公式（1）中，G表示氢原子，脂肪族基团，芳基基团或杂环基团；R1表示氨基基团，脂肪氧基团，脂肪族基团，芳基基团或杂环基团；R2表示取代基；A表示杂环基团；m表示0至5的整数；n表示1至4的整数，其中：当n=2时，偶氮颜料是通过R1、R2、A或G形成的二聚体；当n=3时，偶氮颜料是通过R1、R2、A或G形成的三聚体；当n=4时，偶氮颜料是通过R1、R2、A或G形成的四聚体。
• Processed pigment, pigment-dispersed composition, colored photosensitive composition, color filter, liquid crystal display element, and solid image pickup element
  申请人：FUJIFILM Corporation

  公开号：EP2048539A1

  公开（公告）日：2009-04-15

  Provided are a processed pigment excellent in dispersibility and dispersion stability, a pigment-dispersed composition excellent in dispersibility and dispersion stability of a pigment that uses the processed pigment, a colored photosensitive composition using the pigment-dispersed composition, and a color filter having improved color properties that uses the colored photosensitive composition, in which a pigment is covered with at least one of a specific polymer compound selected from the following (SP-1) to (SP-3); (SP-1) A polymer compound having a heterocycle on a side chain, (SP-2) A graft polymer compound having a weight average molecular weight of from 1,000 to 100000, (SP-3) A polymer compound represented by the following formula (3-1), wherein, RC , RD, A1 and P1 respectively represent an organic linkage group, a single bond or a divalent organic linkage group, a monovalent organic group containing such as an organic dye structure, and a polymer skeleton.

  本发明提供了一种分散性和分散稳定性优异的加工颜料、一种使用该加工颜料的分散性和分散稳定性优异的颜料分散组合物、一种使用该颜料分散组合物的彩色感光组合物以及一种使用该彩色感光组合物的颜色特性得到改善的滤色片，其中，颜料被至少一种选自以下(SP-1)至(SP-3)的特定高分子化合物覆盖； (SP-1) 侧链上有杂环的聚合物化合物、 (SP-2) 一种接枝聚合物化合物，其重量平均分子量为 1,000 至 100000、 (SP-3) 下式(3-1)所代表的聚合物化合物、 其中，RC、RD、A1 和 P1 分别代表有机连接基团、单键或二价有机连接基团、含有诸如有机染料结构的一价有机基团和聚合物骨架。
• Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same
  申请人：FUJIFILM Corporation

  公开号：EP2165828A1

  公开（公告）日：2010-03-24

  The present invention provides a resin composition for laser engraving, containing at least an inorganic porous material, a binder polymer, a thermopolymerization initiator and a polymerizable compound; a relief printing plate precursor for laser engraving using the same; a relief printing plate; and a method of producing the relief printing plate.

  本发明提供了一种用于激光雕刻的树脂组合物，其中至少含有一种无机多孔材料、一种粘合剂聚合物、一种热聚合引发剂和一种可聚合化合物；一种用于激光雕刻的浮雕印版前体；一种浮雕印版；以及一种生产浮雕印版的方法。
• PIGMENT DISPERSION COMPOSITION, CURABLE COLOR COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME
  申请人：FUJIFILM Corporation

  公开号：EP2218756A1

  公开（公告）日：2010-08-18

  The present invention provides: a pigment dispersion composition including (A) an organic pigment, (B) a pigment derivative represented by Formula (I) below and (C) a polymer compound having a pigment-adsorptive functional group; a curable color composition including the pigment dispersion composition, a polymerizable compound and a polymerization initiator; and a color filter having a color region formed using the curable color composition and a method for producing the same. Q represents an organic colorant residue; A represents an ethylene group or the like; and R represents a hydroxyl group or a group represented by -NH-A-Z; Z represents -SO3H, -COOH or a salt thereof; and n represents an integer of from 1 to 4. When R represents -NH-A-Z, the structures represented by the two -NH-A-Zs bonded to the triazine ring contained in each of the n partial structures bonded to Q may be the same as each other or different from each other.

  本发明提供：一种颜料分散组合物，包括(A)有机颜料、(B)下式(I)代表的颜料衍生物和(C)具有颜料吸附官能团的高分子化合物；一种可固化颜色组合物，包括该颜料分散组合物、可聚合化合物和聚合引发剂；以及一种具有使用该可固化颜色组合物形成的颜色区域的彩色滤光片及其生产方法。Q 代表有机着色剂残基；A 代表乙烯基或类似基团；R 代表羟基或由-NH-A-Z 代表的基团；Z 代表-SO3H、-COOH 或其盐；n 代表 1 至 4 的整数。 当 R 代表-NH-A-Z 时，与 Q 键合的 n 个部分结构中的每个部分结构所包含的与三嗪环键合的两个-NH-A-Z 所代表的结构可以彼此相同，也可以彼此不同。
• PIGMENT-DISPERSED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, COLOR FILTER, LIQUID CRYSTAL DISPLAY ELEMENT, AND SOLID IMAGE PICKUP ELEMENT
  申请人：FUJIFILM Corporation

  公开号：EP2270110A1

  公开（公告）日：2011-01-05

  A pigment-dispersed composition includes (a) a high-molecular compound containing at least one kind of repeating unit selected from repeating units each represented by the following Formula (I) or (II), (b) a pigment, and (c) an organic solvent, wherein, in Formulae (I) and (II), R1 to R6 each represent a hydrogen atom or another group; X1 and X2 each represent -CO-, -C(=O)O-, -CONH-, -OC(=O)-, or a phenylene group; L1 and L2 each represent a single bond or a divalent organic linking group; A1 and A2 each represent a monovalent organic group; m and n each represent an integer of from 2 to 8; and p and q each represent an integer of from 1 to 100. Also disclosed is a pigment-dispersed composition containing (A) a graft high-molecular polymer in which acrylic acid is copolymerized at a proportion of from 5% by mass to 30% by mass in the main chain thereof, (B) a pigment, and (C) an organic solvent.

  一种颜料分散组合物包括(a)一种高分子化合物，其中至少含有一种选自下式(I)或(II)所代表的重复单元的重复单元；(b)一种颜料；以及(c)一种有机溶剂，其中，在式(I)和(II)中，R1至R6各自代表氢原子或另一个基团；X1和X2各自代表-CO-、-C(＝O)O-、-CONH-、-OC(＝O)-或亚苯基；L1和L2各自代表单键或二价有机连接基团；A1和A2各自代表一价有机基团；m和n各自代表2至8的整数；p和q各自代表1至100的整数。本发明还公开了一种颜料分散组合物，该组合物含有(A)一种接枝高分子聚合物，其中丙烯酸在其主链中的共聚比例为 5%（质量分数）至 30%（质量分数）；(B)一种颜料；以及(C)一种有机溶剂。