| 1203661-01-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1203661-01-1
• 化学式: C₁₈H₂₉NO₆
• 分子量: 355.431
• InChiKey: AUTGQAIKJRISAG-JHJVBQTASA-N

反应信息

• 作为产物：
  描述：

  、 三甲基乙酰氯 在 吡啶 作用下， 生成
  参考文献：
  名称：

  The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors

  摘要：

  Nitrogen-in-the-ring analogues of L-fucose and L-rhamnose were prepared, which feature a spirocyclopropyl moiety in place of the methyl group of the natural sugar. The synthetic route involved a titanium-mediated aminocyclopropanation of a glycononitrile as the key step. Four new spirocyclopropyl iminosugar analogues were generated, which displayed some activity towards L-fucosidase and L-rhamnosidase. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2009.10.010