3-羧基香豆素-Β-D-吡喃葡萄糖醛酸 | 216672-17-2

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 中文名称: 3-羧基香豆素-Β-D-吡喃葡萄糖醛酸
• 中文别名: 3-羧基香豆素-β-D-吡喃葡萄糖醛酸
• 英文名称: 3-Carboxyumbelliferyl-b-D-glucuronide
• 英文别名: 7-[(2S,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy-2-oxochromene-3-carboxylic acid
• CAS: 216672-17-2
• 化学式: C₁₆H₁₄O₁₁
• 分子量: 382.27
• InChiKey: FYKJWPNWCJGLBP-DKQGBHPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  180
• 氢给体数：
  5
• 氢受体数：
  11

文献信息

• Functional assays for cholesterol absorption inhibitors
  申请人：Levitan Diane

  公开号：US20060161994A1

  公开（公告）日：2006-07-20

  The present invention relates to functional assays performed in C.elegans worms that are useful for the identification of NPC1L1 inhibitors. Compositions useful for the performance of such assays are also provided.

  本发明涉及在 虫 蠕虫中进行的、有助于鉴定 NPC1L1 抑制剂的功能测定。本发明还提供了有助于进行此类试验的组合物。
• FUNCTIONAL ASSAYS FOR CHOLESTEROL ABSORPTION INHIBITORS
  申请人：Schering Corporation

  公开号：EP1834180A2

  公开（公告）日：2007-09-19
• BIOCHEMICAL SENSOR FOR QUANTITATIVE SIMULTANEOUS MULTI-SPECIES BACTERIA DETECTION IN SITU
  申请人：Environmental Technology Solutions LLC

  公开号：US20130260417A1

  公开（公告）日：2013-10-03

  Methods for detecting the concentration of one or more target organisms in a water sample. The methods involve adding a tagged reagent to a water sample, wherein the tagged reagent is water soluble; and determining a concentration of at least one bacteria in the water sample based on an intensity of an emission emitted from the water sample in response to exposure to light having a known wavelength. An apparatus including a reaction chamber; a reversible pump, a reagent source comprising a fluorophore-tagged reagent, a light source, an optical detector disposed to detect fluorescence emitted from the reaction chamber in response to light emitted from the light source; a processor configured to communicate with the reversible pump, the reagent source, the light source, and the optical detector, the processor being configured to determine the concentration of one or more target organisms in a water sample, and optionally transmit the resulting data to a remote location.
• US5510243A
  申请人：——

  公开号：US5510243A

  公开（公告）日：1996-04-23
• [EN] FUNCTIONAL ASSAYS FOR CHOLESTEROL ABSORPTION INHIBITORS<br/>[FR] ESSAIS FONCTIONNELS POUR L'IDENTIFICATION D'INHIBITEURS D'ABSORPTION DU CHOLESTEROL
  申请人：SCHERING CORP

  公开号：WO2006065709A2

  公开（公告）日：2006-06-22

  [EN] The present invention relates to functional assays performed in C.elegans worms that are useful for the identification of NPC1 L1 inhibitors. Compositions useful for the performance of such assays are also provided.
  [FR] La présente invention concerne des essais fonctionnels effectués dans des vers C. elegans, lesquels essais sont utiles pour identifier des inhibiteurs de NPC1L1. L'invention concerne également des compositions utiles pour effectuer ces essais.