pentapropylene glycol | 1167572-53-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: pentapropylene glycol
• 英文别名: 1,3-propanediol pentamer；HO-Ppg5-OH；3-[3-[3-[3-(3-hydroxypropoxy)propoxy]propoxy]propoxy]propan-1-ol
• CAS: 1167572-53-3
• 化学式: C₁₅H₃₂O₆
• 分子量: 308.415
• InChiKey: QCNODSMOZZBAFI-UHFFFAOYSA-N

物化性质

• 沸点：
  431.6±45.0 °C(Predicted)
• 密度：
  1.039±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  21
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  pentapropylene glycol 、 甲基磺酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以83%的产率得到pentapropylene glycol bis-mesylate
  参考文献：
  名称：

  Steroidal bivalent ligands for the estrogen receptor: Design, synthesis, characterization and binding affinities

  摘要：

  Steroidal bivalent ligands for the estrogen receptor (ER) were designed using crystal structures of ER alpha dimers as a template. The syntheses of several 17 alpha-ethynylestradiol-based bivalent ligands with varying linker compositions and lengths are described. The binding affinities of these bivalent ligands for ERa and ER beta were determined. In the two series of bivalent ligands that we synthesized, there is a clear correlation between linker length and binding affinity, both of which reach a maximum at the same tether length. Further studies are underway to explore aspects of bivalent ligand and control compound binding to the ERs and their effects on ER dimer formation; these results will be reported in a subsequent publication. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2009.04.016
• 作为产物：
  描述：

  dibenzyl pentapropylene glycol 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 40.0h， 以100%的产率得到pentapropylene glycol
  参考文献：
  名称：

  Steroidal bivalent ligands for the estrogen receptor: Design, synthesis, characterization and binding affinities

  摘要：

  Steroidal bivalent ligands for the estrogen receptor (ER) were designed using crystal structures of ER alpha dimers as a template. The syntheses of several 17 alpha-ethynylestradiol-based bivalent ligands with varying linker compositions and lengths are described. The binding affinities of these bivalent ligands for ERa and ER beta were determined. In the two series of bivalent ligands that we synthesized, there is a clear correlation between linker length and binding affinity, both of which reach a maximum at the same tether length. Further studies are underway to explore aspects of bivalent ligand and control compound binding to the ERs and their effects on ER dimer formation; these results will be reported in a subsequent publication. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2009.04.016

文献信息

• ANTIMICROBIAL COMPOSITIONS COMPRISING TRIMETHYLENE GLYCOL OLIGOMER AND METHODS OF USING THE COMPOSITIONS
  申请人：Fenyvesi Gyorgyi

  公开号：US20110224307A1

  公开（公告）日：2011-09-15

  Disclosed are antimicrobial compositions, and methods for killing, inhibiting, or preventing the growth of microbes, using trimethylene glycol oligomers or dimers. The trimethylene glycol oligomers and dimers have the formula R(CH 2 CH 2 CH 2 —O—CH 2 CH 2 CH 2 ) n R 1 where R and R 1 are hydroxyl, amine, or ester functionalitiess, and n is 2 or higher. The antimicrobial compositions are useful in personal care and cosmetic compositions

  本发明涉及抗微生物组合物，以及使用三亚甲基二醇低聚物或二聚物杀灭、抑制或防止微生物生长的方法。所述三亚甲基二醇低聚物和二聚物的化学式为R(CH2CH2CH2—O—CH2CH2CH2)nR1，其中R和R1是羟基、胺基或酯基官能团，n为2或更高。所述抗微生物组合物适用于个人护理和化妆品组合物。
• Liquid crystal composition, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device
  申请人：DAI NIPPON PRINTING CO., LTD.

  公开号：US11390810B2

  公开（公告）日：2022-07-19

  A liquid crystal composition containing a side-chain liquid crystal polymer, a polymerizable liquid crystal compound, and a photopolymerization initiator, wherein the side-chain liquid crystal polymer contains a constitutional unit which is represented by the following general formula (I) and a liquid crystal constitutional unit which contains a side chain including a liquid crystal moiety:

  一种液晶组合物，包含侧链液晶聚合物、可聚合液晶化合物和光聚合引发剂，其中侧链液晶聚合物包含由以下通式（I）表示的构型单元和液晶构型单元，液晶构型单元包含包括液晶分子的侧链：
• [EN] AQUEOUS PIGMENT DISPERSION CONTAINING LOW MOLECULAR WEIGHT POLYTRIMETHYLENE ETHER GLYCOL<br/>[FR] DISPERSION AQUEUSE DE PIGMENT CONTENANT DU POLYTRIMÉTHYLÈNE ÉTHER GLYCOL DE FAIBLE MASSE MOLÉCULAIRE
  申请人：DU PONT

  公开号：WO2013028640A3

  公开（公告）日：2013-05-02
• LIQUID CRYSTAL COMPOSITION, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE
  申请人：DAI NIPPON PRINTING CO., LTD.

  公开号：US20210189239A1

  公开（公告）日：2021-06-24

  A liquid crystal composition containing a side-chain liquid crystal polymer, a polymerizable liquid crystal compound, and a photopolymerization initiator, wherein the side-chain liquid crystal polymer contains a constitutional unit which is represented by the following general formula (I) and a liquid crystal constitutional unit which contains a side chain including a liquid crystal moiety: