4-methyl-2-phenyl-2H-indazole | 1338362-91-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-methyl-2-phenyl-2H-indazole
• 英文别名: 4-Methyl-2-phenylindazole
• CAS: 1338362-91-6
• 化学式: C₁₄H₁₂N₂
• 分子量: 208.263
• InChiKey: NCAJSOSJQKPJMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-苯基甘氨酸 在 四丁基氟化铵 、 乙酸酐 、 sodium nitrite 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 17.33h， 生成 4-methyl-2-phenyl-2H-indazole 、 7-methyl-2-phenyl-2H-indazole
  参考文献：
  名称：

  Synthesis of 2H-Indazoles by the [3 + 2] Dipolar Cycloaddition of Sydnones with Arynes

  摘要：

  A rapid and efficient synthesis of 2H-indazoles has been developed using a [3 + 2] dipolar cycloaddition of sydnones and arynes. A series of 2H-indazoles have been prepared in good to excellent yields this protocol, and subsequent Pd-catalyzed coupling reactions can be applied to the halogenated products to generate a structurally diverse library of indazoles.

  DOI：

  10.1021/jo201605v

文献信息

• CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF
  申请人：Dow Corning Toray Co., Ltd.

  公开号：EP1689816A1

  公开（公告）日：2006-08-16
• Curable Silicone Composition and Cured Product Thereof
  申请人：Morita Yoshitsugu

  公开号：US20070225437A1

  公开（公告）日：2007-09-27

  A curable silicone composition includes: (A) an organopolysiloxane represented by the siloxane unit formula (1) given below and having at least two univalent organic groups that contain epoxy groups and are free of aromatic rings: [R 1 3 SiO 1/2 ] a [R 2 2 SiO 2/2 ] b [R 3 SiO 3/2 ] c (where R 1 , R 2 , and R 3 are univalent organic groups, at least two of which are contain epoxy groups and are free of aromatic rings; more than 20 mole % of R 3 are aryl groups; a+b+c & equals; 1; on average, “a” satisfies the following condition: 0≦a≦0.8; on average, “b” satisfies the following condition: 0≦b≦0.8; and, on average satisfies the following condition: 0.2≦c≦1.0); (B) a linear-chain organopolysiloxane having at least two univalent organic groups that contain phenolic hydroxyl groups; and (C) a curing accelerator.
• US7781522B2
  申请人：——

  公开号：US7781522B2

  公开（公告）日：2010-08-24
• [EN] CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF<br/>[FR] COMPOSITION DE SILICONE APTE A LA CUISSON ET SON PRODUIT TRAITE
  申请人：DOW CORNING TORAY SILICONE

  公开号：WO2005044920A1

  公开（公告）日：2005-05-19

  A curable silicone composition includes: (A) an organopolysiloxane represented by the siloxane unit formula (1) given below and having at least two univalent organic groups that contain epoxy groups and are free of aromatic rings: [R13SiO1/2]a [R22SiO2/2]b [R3SiO3/2]c (where R1, R2, and R3 are univalent organic groups, at least two of which are univalent organic groups which contain epoxy groups and are free of aromatic rings; more than 20 mole % of R3 are aryl groups; a + b + c = 1; on average, 'a' satisfies the following condition: 0 ≤ a ≤ 0.8; on average, 'b' satisfies the following condition: 0 ≤ b ≤ 0.8; and, on average, 'c' satisfies the following condition: 0.2 ≤ c ≤ 1.0); (B) a linear-chain organopolysiloxane having at least two univalent organic groups that contain phenolic hydroxyl groups; and (C) a curing accelerator.