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β,δ-Dioxocaproaldehyd-diethylacetal | 28787-33-9

中文名称
——
中文别名
——
英文名称
β,δ-Dioxocaproaldehyd-diethylacetal
英文别名
6,6-Diethoxyhexane-2,4-dione
β,δ-Dioxocaproaldehyd-diethylacetal化学式
CAS
28787-33-9
化学式
C10H18O4
mdl
——
分子量
202.251
InChiKey
BKTMHEDMUAKSAG-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    0.3
  • 重原子数:
    14
  • 可旋转键数:
    8
  • 环数:
    0.0
  • sp3杂化的碳原子比例:
    0.8
  • 拓扑面积:
    52.6
  • 氢给体数:
    0
  • 氢受体数:
    4

文献信息

  • MACROCYCLIC FACTOR XIA INHIBITORS CONDENSED WITH HETEROCYCLES
    申请人:BRISTOL-MYERS SQUIBB COMPANY
    公开号:US20170057961A1
    公开(公告)日:2017-03-02
    The present invention provides compounds of Formula (Ia): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
  • MACROCYCLIC FACTOR XIA INHIBITORS BEARING HETEROCYCLIC GROUPS
    申请人:Bristol-Myers Squibb Company
    公开号:US20180222907A1
    公开(公告)日:2018-08-09
    The present invention provides compounds of Formula (Ia): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
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