1-Ethyl-phenanthridin | 33814-54-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-Ethyl-phenanthridin
• 英文别名: 1-ethyl-phenanthridine；1-Aethyl-phenanthridin；Ethylphenanthridine；1-ethylphenanthridine
• CAS: 33814-54-9
• 化学式: C₁₅H₁₃N
• 分子量: 207.275
• InChiKey: MSGVBGIDFWDWKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  邻溴苯甲醛 、 alkaline earth salt of/the/ methylsulfuric acid 在 铜 作用下， 生成 1-Ethyl-phenanthridin
  参考文献：
  名称：

  Kondo; Uyeo, Chemische Berichte, 1937, vol. 70, p. 1087,1091

  摘要：

  DOI：

文献信息

• Uyeo, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1937, vol. 57, p. 839,846
  作者：Uyeo

  DOI：——

  日期：——
• PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS
  申请人：University Court of The University of Glasgow

  公开号：EP1692130A2

  公开（公告）日：2006-08-23
• [EN] PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS<br/>[FR] COMPOSES AROMATIQUES HETEROCYCLIQUES
  申请人：UNIV GLASGOW

  公开号：WO2005054241A2

  公开（公告）日：2005-06-16

  New classes of heterocyclic aromatic cationic compounds are disclosed, and in particular new classes of phenanthridinium derivatives, most notably dihydro-imidazo-phenanthridinium (DIP) compounds. These findings are based on the reaction of the middle b ring of a phenanthridinium core with primary amines to form DIP compounds (Formula A) or secondary amines to form 2-aminoalkyl phenanthridinium derivatives (Formula B). These reactions can also be applied to other classes of starting compounds which comprise a 6-membered ring aromatic heterocycle having a ring nitrogen and at least one alpha hydrogen atom which can be reacted with a primary or secondary amine.