JX7WH7Zle5 | 2409847-43-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: JX7WH7Zle5
• 英文别名: N'-[[1-(1H-benzimidazol-2-ylmethyl)benzimidazol-2-yl]methyl]-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
• CAS: 2409847-43-2
• 化学式: C₂₉H₃₃N₇
• 分子量: 479.6
• InChiKey: QPPMVBFZIURBHN-SANMLTNESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  88.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Compositions of CXCR4 inhibitors and methods of preparation and use
  申请人：X4 Pharmaceuticals, Inc.

  公开号：US10548889B1

  公开（公告）日：2020-02-04

  The present invention provides compositions and methods of use for treating, preventing, or ameliorating a disease, disorder, or condition associated with a chemokine receptor such as CXCR4.

  本发明提供了用于治疗、预防或改善与化学因子受体（如CXCR4）相关的疾病、紊乱或状况的组合物和使用方法。
• COMPOSITIONS OF CXCR4 INHIBITORS AND METHODS OF PREPARATION AND USE
  申请人：X4 Pharmaceuticals, Inc.

  公开号：US20200253953A1

  公开（公告）日：2020-08-13

  The present invention provides compositions and methods of use for treating, preventing, or ameliorating a disease, disorder, or condition associated with a chemokine receptor such as CXCR4.
• [EN] COMPOSITIONS OF CXCR4 INHIBITORS AND METHODS OF PREPARATION AND USE<br/>[FR] COMPOSITIONS D'INHIBITEURS DE CXCR4 ET MÉTHODES DE PRÉPARATION ET D'UTILISATION
  申请人：X4 PHARMACEUTICALS INC

  公开号：WO2020047410A1

  公开（公告）日：2020-03-05

  The present invention provides compositions and methods of use for treating, preventing, or ameliorating a disease, disorder, or condition associated with a chemokine receptor such as CXCR4.