tetracosan-2-one | 31469-30-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tetracosan-2-one
• 英文别名: 2-Tetracosanone
• CAS: 31469-30-4
• 化学式: C₂₄H₄₈O
• 分子量: 352.645
• InChiKey: YLXYBDHLRCMBAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  25
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tetracosan-2-one 生成 tetracosan-2-one semicarbazone
  参考文献：
  名称：

  Hospital-acquired infections among chronic hemodialysis patients

  摘要：

  The epidemiological characteristics of nosocomial infections among patients requiring chronic hemodialysis, a high-risk and rapidly growing population, have not been fully elucidated. During a 30 month cohort study, rates of bloodstream infections (BSIs), urinary tract infections (UTIs), pneumonia, and diarrhea caused by Clostridium difficile and the distribution of pathogens among hospitalized chronic hemodialysis patients were compared with hospitalized patients not requiring chronic hemodialysis, To identify risk factors for developing a nosocomial infection among chronic hemodialysis patients, a matched case-control study was performed. A total of 1,557 nosocomial infections were detected during 1,317 of 68,361 admissions (2%). Of these, 47 nosocomial infections occurred in chronic hemodialysis patients during 31 of 578 admissions (5%). Nosocomial infections were significantly more frequent among the chronic hemodialysis group (9.1/1,000 patient-days) compared with the non-chronic hemodialysis group (3.8/1,000 patient-days; relative risk [RR], 2.4; 95% confidence interval [CI], 1.8 to 3.2; P < 0.001). UTIs were the most common nosocomial infections among chronic hemodialysis patients, accounting for 47% of all infections in this population. UTIs were significantly more common among chronic hemodialysis patients (4.2/1,000 patient-days) compared with non-chronic hemodialysis patients (0.7/1,000 patient-days; RR, 6.2; 95% CI, 3.8 to 9.5; P < 0.001). Among chronic hemodialysis patients, Candida spp and enterococci were the most common pathogens in contrast to coagulase-negative staphylococci and Staphylococcus aureus among patients not requiring hemodialysis. Using conditional logistic regression, a greater index of comorbidity was significantly associated with nosocomial infections among the chronic hemodialysis population (odds ratio, 3.6; 95% CI, 1.2 to 10.7; P = 0.02), Chronic hemodialysis patients are at a substantially greater risk for developing a nosocomial infection compared with other hospitalized patients. (C) 2000 by the National Kidney Foundation, Inc.

  DOI：

  10.1016/s0272-6386(00)70044-8
• 作为产物：
  描述：

  tetracos-23-en-2-ol 在 {CpRu[P(i-Pr)2(1-Me-4-tBu-imidazol-2-yl)]MeCN}*PF₆ 作用下， 以 丙酮 为溶剂， 反应 86.4h， 以91%的产率得到tetracosan-2-one
  参考文献：
  名称：

  Extensive Isomerization of Alkenes Using a Bifunctional Catalyst:  An Alkene Zipper

  摘要：

  Catalyzed movement of alkene double bonds up to 30 positions has been accomplished using a catalyst featuring a cationic CpRu fragment and bifunctional imidazolylphosphine. The basic nitrogen of the latter is thought to deprotonate coordinated alkene intermediates reversibly, facilitating isomerization between terminal and (E)-alkenes and accelerating conversions by factors of up to 1 x 10(4).

  DOI：

  10.1021/ja073457i

文献信息

• Production of Distillate Fuels from Biomass-Derived Polyoxygenates
  申请人：VIRENT, INC.

  公开号：US20130263498A1

  公开（公告）日：2013-10-10

  The present invention provides methods, reactor systems and catalysts for converting biomass and biomass-derived feedstocks to C 8+ hydrocarbons using heterogenous catalysts. The product stream may be separated and further processed for use in chemical applications, or as a neat fuel or a blending component in jet fuel and diesel fuel, or as heavy oils for lubricant and/or fuel oil applications.

  本发明提供了将生物质和生物质衍生原料转化为C8+烃的方法、反应器系统和催化剂，使用的是异质催化剂。产品流可以分离并进一步加工，用于化学应用，或作为纯净燃料或混合组分用于喷气燃料和柴油燃料，或作为润滑剂和/或燃油应用的重质油。
• CATALYSTS FOR HYDRODEOXYGENATION OF OXYGENATED HYDROCARBONS
  申请人：Blank Brian

  公开号：US20140051872A1

  公开（公告）日：2014-02-20

  The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.

  本发明提供了将含氧碳氢化合物转化为含氧化合物的催化剂、方法和反应器系统。该发明包括利用含有钯、钼、锡和钨的催化剂从含氧碳氢化合物（如碳水化合物、糖类、糖醇、糖降解产物等）生产环氧醚、单氧化物、双氧化物、酮、醛、羧酸和醇的方法。生产的含氧化合物可用于生产液体燃料、化学品和其他产品。
• [EN] BIOFUELS VIA HYDROGENOLYSIS-CONDENSATION<br/>[FR] BIOCOMBUSTIBLES OBTENUS PAR HYDROGÉNOLYSE-CONDENSATION
  申请人：SHELL OIL CO

  公开号：WO2011082001A1

  公开（公告）日：2011-07-07

  A method comprises a providing a carbohydrate; reacting the carbohydrate directly with hydrogen in the presence of a hydrogenolysis catalyst to produce a reaction product comprising a polyol; and then processing at least a portion of the reaction product to form a fuel blend.

  一种方法包括提供一个碳水化合物；在氢解催化剂的存在下直接将碳水化合物与氢反应，以产生包含多元醇的反应产物；然后处理至少反应产物的一部分以形成燃料混合物。
• Tailored Oils Produced from Recombinant Oleaginous Microorganisms
  申请人：Franklin Scott

  公开号：US20120203018A1

  公开（公告）日：2012-08-09

  Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.

  本文提供了用于在重组微生物中生产油、燃料、油脂化学品和其他化合物的方法和组合物，包括含油微生物和低成本培养这种微生物的方法。含有外源基因编码脂肪酶、蔗糖转运蛋白、蔗糖转化酶、果糖激酶、多糖降解酶、酮基酰基-ACP合酶酶、脂肪酰-ACP硫酯酶、脂肪酰-CoA/醛还原酶、脂肪酰-CoA还原酶、脂肪醛还原酶、脂肪酸羟化酶、不饱和酶、脂肪醛脱羰基酶和/或酰基载体蛋白的微藻细胞可用于制造可再生柴油、生物柴油和可再生喷气燃料，以及油脂化学品，如功能流体、表面活性剂、肥皂和润滑剂。
• Synthesis of Liquid Fuels and Chemicals from Oxygenated Hydrocarbons
  申请人：Virent, Inc.

  公开号：EP2698416A2

  公开（公告）日：2014-02-19

  Processes and reactor systems are provided for the conversion of oxygenated hydrocarbons to hydrocarbons, ketones and alcohols useful as liquid fuels, such as gasoline, jet fuel or diesel fuel, and industrial chemicals. The process involves the conversion of mono-oxygenated hydrocarbons, such as alcohols, ketones, aldehydes, furans, carboxylic acids, diols, triols, and/or other polyols, to C4+ hydrocarbons, alcohols and/or ketones, by condensation. The oxygenated hydrocarbons may originate from any source, but are preferably derived from biomass.

  本发明提供了将含氧碳氢化合物转化为可用作汽油、喷气燃料或柴油等液体燃料和工业化学品的碳氢化合物、酮类和醇类的工艺和反应器系统。该工艺包括将单氧碳氢化合物，如醇、酮、醛、呋喃、羧酸、二元醇、三元醇和/或其他多元醇，通过缩合转化为 C4+ 碳氢化合物、醇和/或酮。含氧烃可来自任何来源，但最好来自生物质。